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Microcalcification on mammogram is considered an early sign of breast cancer (BC)
.
Recently, the British Journal of Cancer, an authoritative journal in the field of oncology, published a research article in which researchers assessed the association between microcalcification foci and overall and subtype-specific BC risk
.
In addition, the researchers analyzed how the density (MD) on mammograms affects the association between microcalcifications and the risk of BC
.
The researchers used a prospective cohort of Swedish women (n = 53,273) who had comprehensive information on BC risk factors and mammograms
.
Researchers used computer-aided detection system and STRATUS method to measure the total number of microcalcifications and MD
.
Features of microcalcifications and breast cancer
A total of 676 women in the study were diagnosed with BC cases
.
Compared with women without microcalcifications, the risk ratio [HR] of women with more than 3 microcalcifications was 2.
17 (95% confidence interval [CI]=1.
diagnosis
It can be seen that microcalcification foci is an independent risk factor for BC, and the estimated risk of premenopausal women is higher
.
In postmenopausal women, the association between microcalcification foci and BC is similar to baseline MD
.
Microcalcification foci are an independent risk factor for BC, and premenopausal women have a higher estimated risk
Original source:
Shadi Azam.
et al.
