BrainPathol: Scientists have identified a biomarker used to diagnose a particular neurodegenerative disease, SAFB1.

In a study published in the international journal, scientists from the University of Bristol and others have discovered a new type of pathology mechanism that exists during the onset of a variety of human neurodegenerative diseases, including Huntington's diseasePHOTO SOURCE: The researchers reveal how protein expression called proteins occur in the body of people with spinal microcephaly disorders ( ) and Huntington's disease , or is expected to serve as a common biomarker for the treatment of diseases with similar genetic backgroundsThe researchers say it is an important protein that controls gene regulation in the brain and is structurally similar to other proteins associated with age-related neurodegenerative diseasesIn the study, the researchers wanted to see whether proteins are directly related to the development of specific neurodegenerative diseases and then their analysis of expression in brain tissue after the death of patients with cerebral palpitations, multiple sclerosis, Parkinson's disease and control individuals found abnormal expression in nerve cells in the brain regions associated with cerebellum disorder and Huntington's diseaseSpinal alyocytosis and Huntington's disease are associated with a particular pathological manifestation, known as polyglutamamine dilation (amino acid repetition), which only occurs in both diseases, but the researchers did not find the same pathological manifestations in the body of patients with Parkinson's disease or multiple sclerosisThe researchers say the findings highlight a previously unknown mechanism for inducing diseases and may therefore serve as a diagnostic marker for diagnosing polyglutamamine dilated diseases such as Huntington's diseaseThe next step for researchers will also continue to delve into whether inhibited expression is expected to help improve patient performance, as the researchers will also study other neurodegenerative diseases, including Alzheimer's disease() Original origin: ():