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Even for those who have never been infected with SARS-CoV-2, life>
The study, conducted by a team led by researchers at Massachusetts General Hospital, is published in the journal Brain, Behavior and Immunity
In addition to causing staggering numbers of infections and deaths, the COVID-19 pandemic has caused severe social and economic disruption, affecting the lives of large numbers of the world's population in a number of ways
To better understand the impact of the pandemic on the brain and mental health, the researchers analyzed brain imaging data, conducted behavioral tests, and collected blood samples from multiple uninfected volunteers -- in an effort to limit the spread of the pandemic , 57 before lockdown/stay-at-home measures and 15 after
Post-confinement study participants showed increased levels of two neuroinflammatory markers in the brain, translocin (measured with positron emission tomography) and inositol (measured with magnetic resonance spectroscopy), compared with pre-confinement participants.
Those who reported a heavier burden of symptoms related to emotional, mental and physical fatigue showed higher levels of transporters in certain brain regions than those who reported few or no symptoms
"Despite the explosion of the research literature on COVID-19, the impact of pandemic-related social and life>
Senior author Marco L.
The findings also further support the idea that stressful events may be accompanied by brain inflammation, Loggia added
