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Brain Connectivity: Central structure-function connection mismatch after mild traumatic brain injury

 Last Update: 2021-03-21
 Source: Internet
 Author: User

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Mild traumatic brain injury (light TBI) exhibits abnormal brain network topology related to cognitive dysfunction.

62 cases of mild head injury patients (30 cases were original samples, followed up for 3-12 months; 32 cases were independent duplicate samples) and 37 healthy controls.

In subacute mild TBI, most of the global network characteristics in SCN and FCNs remain unchanged, while the overall efficiency and characteristic path length of SCN decrease during follow-up.

According to the node weighting degree, efficiency and centrality characteristics of FCN (A and C) and SCN (B and D), the central area of the acute mild TBI group and the control group was determined.

The relationship between network characteristics and neuropsychological performance.

Mild TBI affects the relationship between SCN and FCN, and the SC-FC coupling strength can be used as a potential biomarker for predicting the long-term prognosis after injury.

Decoupling of structural and functional connectivity in hubs and cognitive impairment after mild traumatic brain injury in this message

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