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BRAIN: 7T MRI to detect the long-term evolution of MS hoop lesions

 Last Update: 2021-03-21
 Source: Internet
 Author: User

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Recent data indicate that there is a ring of iron-containing microglia around the white matter lesions of multiple sclerosis, which is called hoop lesions, which means that the patient's disease course is more serious and there is a tendency to develop progressive multiple sclerosis.

The study is a prospective longitudinal cohort study, recruiting 33 patients (17 females, 30 relapsing-remitting patients, 3 secondary progressive multiple sclerosis), with a median age of 36.

Figure 1 The development of IRL and the previous destruction of the blood-brain barrier.

The study proved that the iron ring around multiple sclerosis lesions showed different volume dynamics and increased neurodegeneration in and around the lesion.

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