Br J Surg: A random clinical study of laparoscopic colorectal cancer surgery for continuous abdominal incision plane blocking, epidural analgesia, or patient-controlled analgesic

Background and objectivelaparoscopythe optimal analgesic regimen afterrectal cancersurgery is not clearThe purpose of this study is to explore the analgesic effect strain oflaparoscopiccolorectal cancersurgery for continuous abdominal incision plane blocking, epidural analgesia, or patient self-controlled analgesicmethodcolorectal cancersurgery patients were randomly divided into three groups: whole hemp joint abdominal incision plane block anesthesia (TAP group), whole hemp joint pluriscose epidural anesthesia (TEA group) and standard whole hemp (GA group)The main indicator is hospital staySecondary indicators includestomachintestinal dynamics, pain scores, and plasma cytokine levels A total of 180 patients were involved in the study results, and 165 patients completed the trial Intentional treatment analysis showed that the hospital stay in the TEA group was significantly longer than that in the TAP group and GA group (4.1 (95% CI: 3.8 to 4.3) days, the tap group median ed3.1 (95% CI: 3.0 to 3.3) days and the GA group median 3.3 (95% CI: 3.2 to 3.6) days; the tap group had an early first exhaust time (P 0?) 001)。 When coughing, the visual simulation scale (VAS) score for tap and TEA groups is lower than that of the GA group (P 0.001) Tap group plasma vascular endothelial growth factor C, leukocyte interleukin 6, epinephrine and cortisol levels decreased significantly concluded that sustained abdominal incision plane blockan analgesicnot not only improves stomach intestinal power, but also shortens hospital stay, which is related to reduced demand for opioids and reduced surgical stress response