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Br J Dermatol: Systemic treatment of psoriasis is not just one network meta-analysis after another

 Last Update: 2022-08-11
 Source: Internet
 Author: User

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In recent years, the number of systemic therapies, including biologics, for the treatment of psoriasis has rapidly increased, requiring up-to-date and comprehensive comparative effectiveness studies to aid clinical decision-maki.

In this issue of the BMJ Gulimi et .

First, the authors concluded that there was a high degree of duplication of so many NMAs published on the same research question -- an average of 3 per year for 15 years -- with an increasing rate of publication over ti.

Second, the authors point out that the ranking of treatments varies between NMAs, even if they were published in the same ye.

Another potential explanation for the inconsistent results between NMAs is that there may be biases related to industry fundi.

statistics

In the end, studies were selective about the outcomes assessed: many studies focused only on efficacy, limited to short-term outcomes, and did not consider safe.

This publication draws attention to the overuse of NMAs in the systemic treatment of psorias.

Source: Leonardi-Bee J, Drucker AM, Systemic treatments for psoriasis: not another network meta-analysis! Br J Dermatol 2022 May 03;

Leonardi-Bee J, Drucker AM, Systemic treatments for psoriasis: not another network meta-analysis! Br J Dermatol 2022 May 03;

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