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Two previous randomized controlled trials have proved that intravenous thrombolysis is effective and safe for patients with acute ischemic stroke more than 4.
5 hours after the onset of symptoms or the last known symptoms (LKW).
In the United States, the clinical experience of using CT perfusion (CTP) to screen patients is limited.
Therefore, the American scholar Lester Y Leung and others initiated a "delayed thrombolysis" program, using CTP to assist in screening, for stroke patients after waking (known LKW over 4.
5 hours, or unknown LKW time 4.
5 to 24 hours).
Teplase intravenous thrombolytic therapy.
The research results will be announced at the LB P1.
Late-Breaking Science Posters special session of the International Stroke Conference 2021 (ISC2021).
Author: Medical team doctors report NMT NMT ISC finishing compiler, please do not reprint without authorization.
Research Introduction The researchers promoted the medical records of acute stroke patients at the Boston Comprehensive Stroke Center from February to October 2020 to screen patients for advanced thrombolytic therapy.
The main results were demographic characteristics, time from onset to treatment (OTT), NIHSS scores at admission and 24 hours, imaging findings, clinical status at discharge, and bleeding complications.
Main findings ➤ Of the 224 acute stroke patients, 8 (50% women) received intravenous thrombolysis 4.
5 to 24 hours after LKW.
The median age was 76(±12) years old.
The median OTT was 617.
5 minutes (±457.
5, range 329-1030 minutes).
The median NIHSS score at admission was 5 (±7.
5, range 2-13). ➤ One patient had a large vessel occlusion (basal artery) and could not undergo thrombectomy (not able to obtain vascular access).
In all cases, CTP showed little or no infarction on the cerebral blood volume chart.
The 24-hour median NIHSS score was 2 (±6.
5, range 0-10); except for one patient, the NIHSS score of all patients decreased.
3 pontine infarctions, 1 internal capsule infarction, 1 multifocal infarction, 1 retinal infarction, 2 negative DWI imaging (1 suspected pontine infarction, 1 basal parietal infarction).
Except for one patient with persistent hemiplegia, all patients returned to normal after discharge without bleeding complications.
Conclusion Early use of CTP to screen patients with advanced thrombolysis (4.
5-24 hours after the onset) shows that this treatment may be safe and has a good clinical outcome.
Yimaitong compiled from: Late Presenter Thrombolysis for Ischemic Stroke: CT Perfusion for Patient Selection Between 4.
5 to 24 Hours After Stroke Onset.
Yimaitong ISC2021 special report long press the QR code to follow ☟☟☟ or click "read original" to see more ISC 2021 special related content!
5 hours after the onset of symptoms or the last known symptoms (LKW).
In the United States, the clinical experience of using CT perfusion (CTP) to screen patients is limited.
Therefore, the American scholar Lester Y Leung and others initiated a "delayed thrombolysis" program, using CTP to assist in screening, for stroke patients after waking (known LKW over 4.
5 hours, or unknown LKW time 4.
5 to 24 hours).
Teplase intravenous thrombolytic therapy.
The research results will be announced at the LB P1.
Late-Breaking Science Posters special session of the International Stroke Conference 2021 (ISC2021).
Author: Medical team doctors report NMT NMT ISC finishing compiler, please do not reprint without authorization.
Research Introduction The researchers promoted the medical records of acute stroke patients at the Boston Comprehensive Stroke Center from February to October 2020 to screen patients for advanced thrombolytic therapy.
The main results were demographic characteristics, time from onset to treatment (OTT), NIHSS scores at admission and 24 hours, imaging findings, clinical status at discharge, and bleeding complications.
Main findings ➤ Of the 224 acute stroke patients, 8 (50% women) received intravenous thrombolysis 4.
5 to 24 hours after LKW.
The median age was 76(±12) years old.
The median OTT was 617.
5 minutes (±457.
5, range 329-1030 minutes).
The median NIHSS score at admission was 5 (±7.
5, range 2-13). ➤ One patient had a large vessel occlusion (basal artery) and could not undergo thrombectomy (not able to obtain vascular access).
In all cases, CTP showed little or no infarction on the cerebral blood volume chart.
The 24-hour median NIHSS score was 2 (±6.
5, range 0-10); except for one patient, the NIHSS score of all patients decreased.
3 pontine infarctions, 1 internal capsule infarction, 1 multifocal infarction, 1 retinal infarction, 2 negative DWI imaging (1 suspected pontine infarction, 1 basal parietal infarction).
Except for one patient with persistent hemiplegia, all patients returned to normal after discharge without bleeding complications.
Conclusion Early use of CTP to screen patients with advanced thrombolysis (4.
5-24 hours after the onset) shows that this treatment may be safe and has a good clinical outcome.
Yimaitong compiled from: Late Presenter Thrombolysis for Ischemic Stroke: CT Perfusion for Patient Selection Between 4.
5 to 24 Hours After Stroke Onset.
Yimaitong ISC2021 special report long press the QR code to follow ☟☟☟ or click "read original" to see more ISC 2021 special related content!
