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Boehringer Ingelheim will start a new collaboration with Thoeris to advance the first-of-its-kind therapy for the treatment of urea cycle disorders (UCD), regardless of the underlying single-gene cause.
Ingelheim, Germany and Vienna, Austria, November 3, 2021 /PRNewswire/ - Boehringer Ingelheim and Thoeris announced a collaboration and licensing agreement to study a new and first-of-its-kind treatment for urea cycle disorders (UCD)
"The new UCD treatment developed by Thoeris can detoxify excessive ammonia levels by promoting pathways in the body to control disease symptoms
“Strengthening emerging medical sciences to provide new therapies that change medical practice and improve the quality of life of patients is a key element of Boehringer Ingelheim’s strategy,” said Dr.
This collaboration stems from the commitment of the Boehringer Ingelheim Transboundary Research (RBB) team in the therapeutic field, which is the "innovation radar" of Boehringer Ingelheim's R&D department to explore unknown scientific fields
In patients with UCD, the absence or defect of one of several proteins involved in ammonia degradation will lead to hyperammonemia and the accumulation of toxic ammonia concentration in the body, which is related to acute pathological effects, such as cerebral edema, lethargy, neurological dysfunction and potential Death
Boehringer Ingelheim
Boehringer Ingelheim is committed to researching breakthrough therapies aimed at improving the health of humans and animals