BMJ Sub-Journal: Chinese scholars found that drinking more coffee reduces the risk of prostate cancer in men

Written | Edited by Wang Cong | Typeset by Wang Duoyu | Shui Chengwen A number of studies in the past few years have shown that drinking more coffee can bring many health benefits.
For example, drinking coffee is associated with a lower relative risk of liver cancer, bowel cancer, and breast cancer
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According to the latest forecast data released by the International Agency for Research on Cancer (IARC) of the World Health Organization, there will be 1.
41 million new male prostate cancers worldwide in 2020, which has become the second highest incidence of malignant tumors in men worldwide (behind lung cancer with 144 Million)
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Three-quarters of prostate cancer cases occur in developed countries in Europe and America, but since the 1970s, new cases of prostate cancer have risen sharply in Asian countries including Japan, Singapore, and China
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In 2015, the incidence of prostate cancer in Shanghai surpassed that of liver cancer for the first time, and it became the fourth highest incidence of male malignant tumors in Shanghai, which is close to developed countries in Europe and the United States, seriously threatening the lives and health of men
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Wang Kefeng and others from Shengjing Hospital of China Medical University published in BMJ Open the title: Coffee consumption and risk of prostate cancer: a systematic review and meta-analysis Thesis [1]
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The study included 16 prospective cohort studies of 57,732 cases of prostate cancer and found that higher coffee consumption was significantly associated with a lower risk of prostate cancer
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This study shows that increasing coffee intake may reduce the risk of prostate cancer
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Previous studies have shown that coffee drinking is associated with lowering the relative risk of liver cancer, bowel cancer, and breast cancer, but so far, there is no conclusive evidence that coffee drinking has a potential role in reducing the risk of prostate cancer
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To study the association between coffee intake and prostate cancer risk, the research team searched a database of related cohort studies published as of September 2020
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Finally, 16 studies were included, of which 7 were in North America, 7 were in Europe, and 2 were conducted in Japan.
The total cohort exceeded 1 million men, of which 57,732 had prostate cancer
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Statistical analysis showed that, compared with low coffee consumption (less than 2 cups per day), people with high coffee consumption (two cups or more per day) were associated with a 9% reduction in the risk of prostate cancer.
The risk of cancer is reduced by 1%
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Further refinement of the analysis of local and advanced prostate cancer shows that compared with low coffee consumption (less than 2 cups per day), people with high coffee consumption (two cups or more per day) have a 7% lower risk of local prostate cancer, and advanced and advanced prostate cancer.
The risk of fatal prostate cancer is reduced by 12%-16%
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Overall, as the number of coffee cups consumed daily increases, the risk of prostate cancer decreases.
The research team believes that the caffeine in coffee can improve glucose metabolism, has anti-inflammatory and antioxidant effects, and can affect the level of sex hormones.
Coffee These effects may affect the occurrence, development and progression of prostate cancer
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In general, this study suggests that increased coffee consumption may be related to lowering the risk of prostate cancer
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However, it is still necessary to further study to determine the underlying mechanism and the key active substances that play a role
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If it can be further proved that the association between coffee consumption and the risk of prostate cancer is causal, it may encourage men to increase coffee consumption to reduce the risk of prostate cancer
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In addition, a number of recent studies have shown that drinking coffee is related to reducing the risk of disease
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Drink more coffee to reduce the risk of chronic diseases On July 23, 2020, the New England Journal of Medicine (NEJM), the first of the four major medical journals, published a review paper titled: Coffee, Caffeine, and Health [2]
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The paper pointed out that a large amount of evidence suggests that drinking coffee does not increase the risk of cardiovascular disease and cancer, and drinking 3 to 5 cups of coffee a day is associated with a reduction in the risk of several chronic diseases
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Drink more coffee to increase the survival time of patients with colorectal cancer.
On September 17, 2020, the Mayo Medical Center, Dana-Farber Cancer Institute and other top international medical research institutions published a title in the top medical journal JAMA Oncology.
: Research paper of Association of Coffee Intake With Survival in Patients With Advanced or Metastatic Colorectal Cancer [3]
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The research team further analyzed the observation data of a large clinical trial of colorectal cancer patients and found that among the 1171 patients with metastatic colorectal cancer who received treatment, patients who drank 2-3 cups of coffee a day had a longer overall survival.
The risk of deterioration is lower, and patients who drink 4 cups of coffee a day benefit more
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Drink more coffee to reduce liver cancer-related mortality.
On August 14, 2020, a number of research institutions in Australia collaborated and published a titled: Estimates of the global reduction in liver disease-related mortality with in Alimentary Pharmacology and Therapeutics.
increased coffee consumption: an analysis of the Global Burden of Disease Dataset [4]
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The paper analyzes the global burden of disease data set and shows that as coffee intake increases, liver cancer-related mortality decreases globally.
Specifically, if everyone in the world drinks at least two cups of coffee a day, the world’s The number of deaths due to liver cancer will be reduced by more than 450,000.
If everyone drinks at least four cups of coffee a day, the number of deaths due to liver cancer will be reduced by more than 720,000
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Special reminder: This article only interprets and reports relevant research papers truthfully, and does not constitute any purchase and use advice
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Paper link: 1.
https://bmjopen.
bmj.
com/content/11/2/e0389022.
https:// /jamaoncology/article-abstract/27702624.
https://onlinelibrary.
wiley.
com/doi/full/10.
1111/apt.
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