BMC Cancer: Prospective study with up to 10 years of follow-up confirms that younger women with non-metastatic breast cancer have worse prognosis

Previous studies have shown that young age (<40 years) is an independent risk factor for poor outcomes in women with breast cancer
.

Recently, the BMC Cancer journal published the results of a prospective study with a follow-up of up to 10 years, evaluating the difference in survival between women aged ≥40 and <40 years with non-metastatic breast cancer, and also exploring tumor characteristics and molecular markers that affect survival.

Previous studies have shown that young age (<40 years) is an independent risk factor for poor outcomes in women with breast cancer

Between July 2011 and May 2014, a total of 119 patients were recruited into this study
.

The median age of all patients was 44 years (2776 years)

Between July 2011 and May 2014, a total of 119 patients were recruited into this study

Median follow-up was 96 months, with a range of 13 to 122 months

The 10-year DFS rate was 90% for patients ≥40 years and 70.
4% for patients <40 years (p = 0.
004)
.

The 10-year DFS rate was 90% for patients ≥40 years and 70.
4% for patients <40 years (p = 0.
004)
.

The 10-year DFS rate was 90% for patients ≥40 years and 70.

In stage I patients, the recurrence rates were 30% and 3.
6% (p=0.
016), respectively, in patients ≥40 years old and <40 years old; in stage II patients, 22.
8% and 9.
7%, respectively (p=0.
116); and in stage III patients, respectively 35.
7% and 23.
1% (p=0.
402) 

In stage I patients, the recurrence rates were 30% and 3.
6% (p=0.
016), respectively, in patients ≥40 years old and <40 years old; in stage II patients, 22.
8% and 9.
7%, respectively (p=0.
116); and in stage III patients, respectively 35.
7% vs 23.
1% (p=0.
402)  in stage I patients, 30% vs 3.
6% (p=0.
016) in patients ≥40 years old and <40 years old; 22.
8% and 9.
7% in stage II patients, respectively (p=0.
116); Stage III 35.
7% and 23.
1%, respectively (p=0.
402) 

In conclusion, this prospective study confirms that young age (<40 years) is a poor prognostic factor in patients with non-metastatic breast cancer
.

In conclusion, this prospective study confirms that young age (<40 years) is a poor prognostic factor in patients with non-metastatic breast cancer
.

This prospective study confirms that young age (<40 years) is an unfavorable prognostic factor in patients with non-metastatic breast cancer

Original source:

Bouferraa Y, Haibe Y, Chedid A, Jabra E, Charafeddine M, Temraz S, Mukherji D, El Saghir N, Shamseddine A.

Bouferraa Y, Haibe Y, Chedid A, Jabra E, Charafeddine M, Temraz S, Mukherji D, El Saghir N, Shamseddine A.
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