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Central point: Children with a history of central venous catheter (CVC)-related thromboembolism are at increased risk of recurrence of venous thromboembolism; subsequent placement of central venous catheters using full-dose anticoagulation as secondary prevention is associated with a 65% reduction in thromboembolism .
Central point: Children with a history of central venous catheter (CVC)-related thromboembolism are at increased risk of recurrence of venous thromboembolism; subsequent placement of central venous catheters using full-dose anticoagulation as secondary prevention is associated with a 65% reduction in thromboembolism .
This is a single-center retrospective study to evaluate the efficacy of secondary prevention in children with a history of CVC-VTE, and to determine the efficacy of patients ≤19 years of age with a history of index CVC-VTE during 2003-2013 Risk factors associated with recurrent VTE
Researchers collected relevant data including clinical and demographic factors, subsequent CVC placement, secondary prevention strategies, recurrent VTE and bleeding
The correlation between the number of CVC and the incidence of non-thrombotic events
The correlation between the number of CVC and the incidence of non-thrombotic eventsA total of 373 children with a history of index CVC-VTE were included, of which 239 (64.
17.
The correlation between the presence or absence of CVD and the incidence of thrombotic events
The correlation between the presence or absence of CVD and the incidence of thrombotic eventsThe use of full-dose anticoagulants as secondary preventive measures is associated with a reduction in the odds ratio of recurrent CVC-VTE (OR 0.
The use of full-dose anticoagulant as a secondary preventive measure is related to the reduction in the odds ratio of recurrent CVC-VTE
In summary, children with a history of CVC-VTE have an increased risk of recurrent VTE
Children with a history of CVC-VTE have an increased risk of recurrent VTE
Original source:
Helen Havens Clark, Lance Ballester, Hilary B Whitworth, et al.
Prevention of Recurrent Thrombotic Events in Children with Central Venous Catheter-Associated Venous Thrombosis
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