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Blood Cancer J: The value of the MASS staging system in the prognosis of the new diagnosis of multiple myeloma

 Last Update: 2022-09-30
 Source: Internet
 Author: User

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To guide treatment decisions for multiple myeloma (MM), there are multiple risk stratification systems in place to distinguish between different risk levels in patients at the time of diagnosis, including ISS and R-ISS
。 R-ISS includes elevated lactate dehydrogenase (LDH) and high-risk cytogenetic abnormalities (HRCA) such as del(17p), t(4;14), and t(14;16), but the influence or weight of various baseline risk factors in estimating outcomes in MM patients may change as MM treatment patterns shift, such as other high-risk cytogenetic abnormalities that are partially not included in R-ISS (e.

In order to further test the prognostic value of the MASS staging system in newly diagnosed MM patients in China, Professor Dai Yun and Professor Jin Fengyan of the First Hospital of Jilin University led the analysis of clinical retrospective data of MM patients in 7 centers in China from November 27, 2009 to November 20, 2019, and the results of the study were published in the Blood Cancer Journal
.

References

Peiyu Yang, Fan Zhou, Yujun Dong,et al.

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