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Penile cancer (PeCa) patients had a better 5-year cancer-specific survival rate (81%)
.
However, the 5-year cancer-specific survival rate for patients with lymph node metastases (LNM) averaged 56%
Invasive nodule staging is required in the cN0 inguinal pelvis for early detection of these metastases to improve survival
Recently, researchers from the Netherlands published an article in the journal BJU Int.
They used dynamic sentinel node biopsy (DSNB) features to establish additional inguinal lymph node metastases after completion of inguinal lymph node dissection (ILND) in patients with positive DSNB.
(LNM) prediction model with the aim of identifying patient populations that may be missed by ILND
.
The study population was drawn from seven European centers and included 407 patients with DSNB-positive penile cancer who subsequently underwent ILND
.
The researchers conducted a retrospective study of their groin pelvis
RESULTS: Among the positive DSNBs, 64 patients (16%) had additional LNM at ILND
.
Number of positive nodules with positive DSNB (odds [OR] 2.
Calibration plot of the final model
Calibration plot of the final modelIn conclusion, there is a small subset of clinically significant inguinal pelvises with additional LNM after completion of ILND in DSNB-positive patients
.
Although DSNB features were associated with additional LNM, they did not improve ILND selection for the inguinal pelvis
There is a small subset of clinically significant inguinal pelvises with additional LNM present after completion of ILND in DSNB-positive patients
Original source:
Original source:Hielke M de Vries, Hack Jae Lee, Wayne Lam et al.
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