Biomaterials: Cell therapy is used to treat enteritis.

October 1, 2020 /--- cell therapy offers hope for treating diseases that do not yet have effective pharmacological solutions.
published in the journal Biomaterials reveals the potential of multi-functional bionic hydrogel systems to enhance the immunomodulation of interstate-charged substation cells.
results so far are encouraging, and the researchers hope to make progress in a multi-functional cell therapy system for inflammatory bowel disease.
they have begun to study ulcerative colitis in animal models.
"The most famous example of cell therapy is regenerative therapy, for example, we've all heard of cartilage cell use in cartilage," said Rosa Hernández, a professor and researcher at CIBER-BBN School of Pharmacy at www.pixabay.com.
regeneration after myocardial infarction or myocardial cell repair of the heart, but our team is evaluating the therapeutic effect of stem cells through side secretion, which is mediated by a series of growth factors and cytokines released by cells.
stem cells may also have the effect of alleviating diseases in all inflammatory diseases, such as ulcerative colitis or Crohn's disease.
, the team of researchers, led by Dr. Rosa Rosannandez and Dr. Manoli Igartua, began a project three years ago to address problems in clinical trials using these stem cells.
While stem cells have the potential to treat these inflammatory diseases in these trials, there are still problems, such as how to quickly remove cells from the body, the risk of tumor occurrence, or their ability to release therapeutic substances, so new technical solutions must be sought.
of the UPV/EHU researchers in the team are Ainhoa Gonzalez-Pujana and Dr. Edorta Santos-Vizcaíno, who recently successfully designed and tested the multifunction system in collaboration with Harvard University in Cambridge, USA.
this way, cells can be prolonged so that they continue to release key cytokines and growth factors to treat these diseases.
addition, the persistence of human cells and the biosecurity of treatment can be improved, (Bioon.com) Source: Celltherapy designed to treaty bowel disease Source: Ainhoa Gonzalez-Pujana et al. Multifunctional biomimetic hydrogel systems to boost the immunomodulatory potential of mesenchymal stromal cells, Biomaterials (2020). DOI: 10.1016/j.biomaterials.2020.120266.