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March 25, 2021 //-- Neurodevelopmental disorders such as autism and schizophrenia have a particularly serious impact on men.
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"We believe that as early as the first trimester of pregnancy, differences in the metabolic requirements of male and female embryos, coupled with dynamic differences in the way male and female placenta respond to environmental factors, have led to an increased risk of male neurodevelopmental disorders.
Beversdorf collaborated with Eldin Jašarevic, assistant professor of pharmacology at the University of Maryland School of Medicine, and a research team on a study that divided 40 mice into four different cohorts.
The team analyzed embryos and placenta at 12.
"Beversdorf said: "This study produced two results about the interaction between maternal stress and dietary supplementation of DHA in early embryos.
Beversdorf said that research is needed in the future to better understand the complex cellular and molecular mechanisms between maternal dietary consumption, chronic stress during pregnancy, placental gene expression, and lasting health outcomes in offspring.
biomedcentral.
com/articles/10.
1186/s13293-020-00356-x">Maternal DHA supplementation influences sex-specific disruption of placental gene expression following early prenatal stress