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    Home > Active Ingredient News > Study of Nervous System > Beyonce: Blood Pressure and Risk of Cognitive Impairment and Dementia

    Beyonce: Blood Pressure and Risk of Cognitive Impairment and Dementia

    • Last Update: 2020-05-30
    • Source: Internet
    • Author: User
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    The link between blood pressure (BP) and the risk of cognitive impairment and dementia remains controversial, due to inconsistent definitions of BP and changes in population characteristicsrecently published a study in the journal Cardiovascular Authority, The researchers looked at PubMed's prospective study of BP's effects on the risk of cognitive impairmentThe researchers conducted dose-response analyses to indicate the presence of linear/nonlinear relationships and assessed the credibility of each meta-analysis based on bias, inconsistency, and inaccurate risk assessment209 of the 31,628 literatures were included in the systematic evaluation, of which 136 were analyzed by researchersOverall, the association between BP and the risk of cognitive impairment and dementia was stronger in middle age than in older adultsMedium-quality evidence suggests that high blood pressure in middle age is associated with a high risk of cognitive impairment of 1.19 to 1.55 timesDose-response analysis of five studies showed that midlife systolic systolic 130mmHg was associated with an increased risk of cognitive impairmentBp in old age, high systolic pressure, low diastolic pressure, large BP variability and low body pressure were all associated with increased risk of dementiaThe use of antihypertensive drugs can reduce the risk of dementia by 21%The U-shaped dose reaction curve indicates that the protective window of diastotic BP is between 90 and 100 mmHg, which has a lower risk of Alzheimer's diseasethus showing that the association between BP and cognitive impairment is age-related and BP-type dependenceAntihypertensive drugs are associated with a reduced risk of dementiaHowever, the optimal BP values and types of prevention of cognitive impairment need further study
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