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Beijing Normal University scholars reveal the important potential of blood RNA modification in clinical detection of pulmonary arterial hypertension

 Last Update: 2022-02-18
 Source: Internet
 Author: User

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To date, scientists have identified more than 150 chemical modifications on eukaryotic non-coding RNAs as well as coding RNAs .

Pulmonary hypertension is a clinical pathophysiological state of excessive pulmonary arterial pressure, which can lead to right heart failure and has a high fatality rate .

We cooperated with the State Key Laboratory of Respiratory Diseases of the First Affiliated Hospital of Guangzhou Medical University , the Institute of Zoology of the Chinese Academy of Sciences and other units , using the high-throughput RNA modification quantitative detection and analysis platform we established earlier , and found that compared with normal people, patients with pulmonary arterial hypertension Blood RNA modifications showed significant changes .

The article is titled "RNA Modification Signature of Peripheral Blood as a Potential Diagnostic Marker for Pulmonary Hypertension" and will be published online in Hypertension (IF: 10.

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