Beans can prevent sepsis

Researchers at Feinstein Institute of Medicine found that a kind of legume commonly used in Chinese dishes can help people avoid the threat of sepsis HMGB1, a DNA protein, mediates the generation of inflammation Inflammation is necessary to keep the body healthy Without inflammation, wounds and infections can never be cured However, inflammation often occurs, which will cause damage to tissues and organs, It causes some diseases such as septicemia About 750000 people are affected by septicemia every year in the United States, and 28-50% of women die of septicemia Septicemia is a life-threatening infection complication, which refers to the invasion of pathogenic bacteria or conditional pathogenic bacteria into the blood circulation, and growth and reproduction in the blood, Acute systemic infection caused by toxin production If the bacteria invading the blood stream are cleared by the human body's defense function, and there is no obvious symptom of toxemia, it is called bacteremia Septicemia with multiple abscesses and a longer course is called pyemia The occurrence of septicemia will damage the body organs, This includes the liver, heart, lung, kidney and brain If there is excessive damage, organ function will not be reversible Therefore, find appropriate methods to identify which inflammation can be terminated, This is important Neutralizing HMGB1 protein concentrations can fight the development of persistent inflammation that can cause damage to body tissues and organs Dr haicao Wang and his colleagues found that mung bean, a legume crop native to India and widely used in Chinese cuisine and traditional medicine, whose extract can reduce the release of HMGB1, "Many traditional herbal medicines have been proved to be effective in the treatment of various inflammatory diseases Now, we have verified the therapeutic potential of another medicinal product, which is mung bean extract," said Dr Wang "We have proved that mung bean extract has a positive effect on septic mice, This suggests that the mung bean may also have a positive therapeutic effect on septic patients Of course, more studies are needed to verify the safety and effectiveness of the drug in humans "