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The water for pharmaceutical production should not contain any bacteria, impurities and other microorganisms.
Therefore, Xiaobian recommends that the managers of the purified water equipment of the pharmaceutical production water preparation system should be familiar with the bacteria detection method of the water used for pharmaceutical production, and regularly test and analyze the water produced by the purified water equipment to ensure that Its water supply is always in excellent condition
.
There are three main methods for the detection of microorganisms in the bacterial detection of purified water equipment for pharmaceutical production: the classical microbial culture method, the instrument method and the conventional method
.
①Classical microbial culture method: The elements of microbial culture method include: type of medium, culture temperature and culture time
.
Cultivation methods include (but are not limited to): sintered dish culture method, flat plate method, membrane filtration method, and the most likely method
.
②The instrumental methods mainly include: direct counting method by microscope, radiation method, impedance method and various biochemical methods
.
A.
The advantage is that the precision is good, the accuracy is high, and the test results can be obtained in a short time, which is conducive to the timely control of the pharmaceutical water system
.
B.
The disadvantage is that the sample needs to be processed manually, the workload is large, the sample processing volume is small, and it is easily restricted by other aspects such as instruments, and the instrument method is destructive to microorganisms, and it cannot further isolate and identify the contaminating bacteria
.
③ conventional methods: pharmacopoeia and literature methods
.
The identification of microorganisms is a highly specialized job that requires a lot of work experience and professional knowledge
.
Mastering the bacteria detection method of purified water equipment for pharmaceutical production is enough to see various phenomena that are not conducive to the water production standards of the equipment, detect the types of polluting bacteria that threaten the quality of water production, and ensure that users can solve problems in a timely manner, combined with good purification.
The operating conditions of the water production equipment ensure that the water production of the system is stable and reliable
.
Therefore, Xiaobian recommends that the managers of the purified water equipment of the pharmaceutical production water preparation system should be familiar with the bacteria detection method of the water used for pharmaceutical production, and regularly test and analyze the water produced by the purified water equipment to ensure that Its water supply is always in excellent condition
.
There are three main methods for the detection of microorganisms in the bacterial detection of purified water equipment for pharmaceutical production: the classical microbial culture method, the instrument method and the conventional method
.
①Classical microbial culture method: The elements of microbial culture method include: type of medium, culture temperature and culture time
.
Cultivation methods include (but are not limited to): sintered dish culture method, flat plate method, membrane filtration method, and the most likely method
.
②The instrumental methods mainly include: direct counting method by microscope, radiation method, impedance method and various biochemical methods
.
A.
The advantage is that the precision is good, the accuracy is high, and the test results can be obtained in a short time, which is conducive to the timely control of the pharmaceutical water system
.
B.
The disadvantage is that the sample needs to be processed manually, the workload is large, the sample processing volume is small, and it is easily restricted by other aspects such as instruments, and the instrument method is destructive to microorganisms, and it cannot further isolate and identify the contaminating bacteria
.
③ conventional methods: pharmacopoeia and literature methods
.
The identification of microorganisms is a highly specialized job that requires a lot of work experience and professional knowledge
.
Mastering the bacteria detection method of purified water equipment for pharmaceutical production is enough to see various phenomena that are not conducive to the water production standards of the equipment, detect the types of polluting bacteria that threaten the quality of water production, and ensure that users can solve problems in a timely manner, combined with good purification.
The operating conditions of the water production equipment ensure that the water production of the system is stable and reliable
.
