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CompilationAspirin
AstraZeneca's Covid-19 vaccine for the beta variant entered Phase 2/3 of clinical trials last year
Another important reason was that there was no significant difference between the immunogenicity of AZD2816 and Vaxzevria
For these two reasons, AstraZeneca will abandon the beta variant and stick with its first-generation vaccine, Vaxzevria
When the beta variant was discovered in October 2020, it represented the most worrying variant of the new coronavirus at the time from an immune escape perspective
Given the small genetic differences between the beta variant and the original SARS-CoV-2 virus, AstraZeneca responded by tweaking its first-generation Vaxzevria vaccine
AstraZeneca dosed the first subjects in a Phase 2/3 clinical trial in June 2021
The rise and fall of AZD2816 offers a cautionary tale for Moderna and Pfizer
AstraZeneca disclosed the termination of AZD2816 in its quarterly report, while revealing the removal of a series of early-stage projects from its pipeline
Reference article: AstraZeneca dumps late-phase, next-gen COVID-19 vaccine, calling time on a beta player in an omicron world