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ASCO2021: Atezolizumab + Bevacizumab combination therapy is beneficial for unresectable liver cancer

 Last Update: 2021-06-16
 Source: Internet
 Author: User

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Art natalizumab + bevacizumab United vs sorafenib median overall survival (OS; 19.

Richard S.

Under the impetus of IMbrave150, the combination of atezolizumab + bevacizumab for first-line unresectable liver cancer patients has obtained global approval, which is based on preliminary analysis results published in May 2020 .

The updated IMbrave150 results presented at the 2021 Gastrointestinal Cancer Symposium are very important.

Compared with sorafenib, other clinically significant benefits observed with atezolizumab combined with bevacizumab include a higher overall response rate (ORR; 30% vs.

Compared with sorafenib, other clinically significant benefits observed with atezolizumab in combination with bevacizumab include a higher overall response rate compared with sorafenib, atezolizumab in combination with bevacizumab Other clinically significant benefits observed with Vallizumab include a higher overall response rate (ORR; 30% vs.

Dr.

Whether the discovery of IMbrave150 points to any biomarkers or clinical parameters can be used to select patients most likely to respond to atezolizumab + bevacizumab
.
Dr.
Finn and others are looking for biomarkers, but this will be a challenge
.
He predicted that a genetic marker or a set of biomarkers would be needed to reliably predict the response of atezolizumab + bevacizumab, rather than a single biomarker
.

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