 Home > Active Ingredient News > Immunology News > Arthritis & Rheumatology: First description of delayed autoinflammatory diseases caused by somatic NLRC4 chimera

Arthritis & Rheumatology: First description of delayed autoinflammatory diseases caused by somatic NLRC4 chimera

 Last Update: 2021-11-12
 Source: Internet
 Author: User

Tags

test alzheimer's disease

epstein barr disease

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Autoinflammatory disease (AID) is a genetic disease of innate immunity, usually beginning in childhood
.

However, several recent studies have found that more and more adults are beginning to suffer from AID

Autoinflammatory disease (AID) is a genetic disease of innate immunity, usually beginning in childhood

Methods: Using Sanger sequencing and next generation sequencing (NGS) genetic method of science research

Results: Researchers from Spain studied a 57 -year-old woman who began to experience recurrent fever, myalgia, arthralgia, diffuse abdominal pain, diarrhea, adenopathy, and systemic inflammation at the age of 47 , using anti- IL- 1 Drugs control these symptoms relatively well

Conclusion: The investigator has determined that the post-zygotic p.

Ser171Phe NLRC4 variant is a reasonable cause of the condition of the admitted patient

Conclusion: The investigator has determined that the post-zygotic p.
Ser171Phe NLRC4 variant is a reasonable cause of the condition of the admitted patient

Source:

First Description of Late-Onset Autoinflammatory Disease Due to Somatic NLRC4 Mosaicism.

Ionescu D, Peñín-Franch A, Mensa-Vilaró A, Castillo P, Hurtado-Navarro L, Molina-López C, Romero-Chala S, Plaza S, Fabregat V, Buján S, Marques J, Casals F, Yagüe J, Oliva B, Fernández-Pereira LM, Pelegrín P, Aróstegui JI.
First Description of Late-Onset Autoinflammatory Disease Due to Somatic NLRC4 Mosaicism.
Arthritis Rheumatol.
2021 Oct 20.
doi: 10.
1002/art.
41999.
Epub ahead of print.
PMID: 34672126 .
in this message

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

Top Quality 99.9% Ritlecitinib Tosylate Immunoregulation API & Inflammation Inhibitor

CAS No.: 2192215-81-7

Pharmacy Grade; Food Grade

$200-250/G FOB

β-Alanine107-95-9

CAS No.: 107-95-9

$1-1.1/KG FOB

High quality Thymosin α1 Pure CAS 62304-98-7 Thymosin Alpha 1 Thymalfasin

CAS No.: 62304-98-7

Pharmacy Grade

$12-15/UNIT FOB

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

80 20 company(94)

united states logo(227)

ups united states(221)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.