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Although genetic factors have a clear impact on rheumatoid arthritis (RA), environmental factors also play a very important role
The study recruited three groups of subjects (50 in each group): 1) early RA patients (in line with the 2010 classification criteria of the American College of Rheumatology/European Rheumatology Association), 2) individuals at risk of developing RA (arthralgia) Patients, RA-related autoantibodies are positive), and 3) healthy controls
There were no significant differences in the three periodontal indicators of early RA patients, high-risk individuals, and healthy controls (BOP P = 0.
The results showed that there were significant differences in the microbial composition of saliva (F=2.
Comparison of the relative abundance of oral microbes among the three groups
It can be seen that compared with healthy controls, the oral microbiomes of early RA patients and RA high-risk individuals are similar, and the oral microbiota of the two is characterized by an increased relative abundance of potential pro-inflammatory bacteria
The characteristic of both oral microbes is the increased relative abundance of potential pro-inflammatory bacteria
Original source:
Original source:Johanna M.
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