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ARD: Safety of ixekizumab in patients with psoriatic arthritis: data from four clinical trials with more than 2000 patient-year exposures

 Last Update: 2022-08-16
 Source: Internet
 Author: User

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Objectives : Ixekizumab is a high-affinity monoclonal antibody that selectively targets interleukin 17A (IL-17A) , and has demonstrated significant efficacy and long-term safety in the treatment of psoriatic arthritis (PsA.

Objectives : Ixekizumab is a high- affinity monoclonal antibody that selectively targets interleukin 17A (IL-17A.

Methods : This was a combined safety analysis of four clinical trials in patients with PsA who received at least one dose of ixekizuma.

Methods This was a combined safety analysis of four clinical trials in patients with PsA who received at least one dose of ixekizuma.

Results A total of 1401 patients were included in the analysis , with a cumulative ixekizumab exposure of 2247/ patient/yea.

Conclusions In this analysis, the overall safety and tolerability of ixekizumab was consistent with the known safety profile in patients with Ps.

Deodhar AA, Combe B, Accioly AP , et a.
Safety of ixekizumab in patients with psoriatic patient arthritis: data from four clinical trials with over 2000-years of exposu.
Annals of the Rheumatic Diseases2022;81:944-95 , et al al Annals of the Rheumatic Diseases commentedhere

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