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Purpose: Ultrasound of temporal artery (TA) and axillary artery (AX) showing incompressible halo signs is recommended for the diagnosis of suspected giant cell arteritis (GCA); however, its value in monitoring GCA disease activity is still poorly understood
.
This study evaluated the sensitivity of newly diagnosed GCA patients to changes in ultrasound halo characteristics and its correlation with disease activity and glucocorticoid (GC) treatment
Purpose: Ultrasound of temporal artery (TA) and axillary artery (AX) showing incompressible halo signs is recommended for the diagnosis of suspected giant cell arteritis (GCA); however, its value in monitoring GCA disease activity is still poorly understood
Methods: A prospective study of ultrasound-confirmed GCA patients undergoing continuous ultrasound evaluation of temporal artery (TA) and axillary artery (AX) at fixed time points .
Record the number of segments with halo and maximum halo inner media thickness (IMT) .
The time point at which the measurement was performed on >80% of the patients was used for analysis .
The halo characteristics at the diagnosis of the disease and the first relapse were compared .
Results: 49 patients were evaluated in 354 visits .
The sensitivity of halo to changes was evaluated at 1 , 3 , 6 , 12, and 24 weeks, showing that TA halo characteristics had a significant standardized average difference between all time points and baseline, but AX halo characteristics were only displayed after the 6th week There is a difference from the baseline .
Having halos TA several segments, the sum and the maximum TA halo IMT following indices significantly correlated: erythrocyte sedimentation rate ( 0.
41 , 0.
44 and 0.
Results: 49 patients were evaluated in 354 visits .
Conclusion: Ultrasound is a useful imaging tool for assessing disease activity and response to treatment in patients with giant cell arteritis
Ponte C, Monti S, Scirè CA , et al .
Ultrasound halo sign as a potential monitoring tool for patients with giant cell arteritis: a prospective analysis.
Annals of the Rheumatic Diseases 2021; 80: 1475-1482.
Ponte C, Monti S, Scirè CA , et al .
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