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    Home > Active Ingredient News > Immunology News > ARD: Prevention of disease flares by risk adaptation stratification of treatment withdrawal in juvenile idiopathic arthritis: results from the PREVENT-JIA trial

    ARD: Prevention of disease flares by risk adaptation stratification of treatment withdrawal in juvenile idiopathic arthritis: results from the PREVENT-JIA trial

    • Last Update: 2022-08-16
    • Source: Internet
    • Author: User
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    Objective : The decision to discontinue treatment in clinical remission of juvenile idiopathic arthritis remains challengi.


    Objectives : The decision to discontinue treatment in clinical remission of juvenile idiopathic arthritis remains challengi.


    Methods : This multicenter trial (PREVENT-JIA) enrolled 119 patients with JIA in clinical remission , 100 of whom entered the intervention phase to continue or discontinue treatment based on S100A12 and hsCRP level.


    METHODS : This multicenter trial ( PREVENT-JIA) enrolled 119 patients with JIA in clinical remission , 100 of whom entered the intervention phase to continue or discontinue treatment based on S100A12 and hsCRP level.


    RESULTS: In the PREVENT-JIA arm, 49 patients experienced seizures, and 45% of discontinued patients experienced seizures within the next 12 mont.


    Conclusion The biomarker-guided treatment withdrawal strategy is feasible in clinical practi.


    Gerss J, Tedy M, Klein A , et a.
    Prevention of disease flares by risk-adapted stratification of therapy withdrawal in juvenile idiopathic arthritis: results from the PREVENT-JIA tri.
    Annals of the Rheumatic Diseases2022; 81: 990-99 , et al Annals of the Rheumatic Diseases81: leave a comment here
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