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ARD: Over 30,000 Data Study: Efficacy of TNF Inhibitors, Abatacept, IL6 Inhibitors, and JAK Inhibitors in Patients with Rheumatoid Arthritis

 Last Update: 2022-09-06
 Source: Internet
 Author: User

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Background: Several second-line treatment options are available to rheumatologists and patients for patients with rheumatoid arthritis who have an inadequate response to conventional synthetic disease-modifying antirheumatic drugs (DMARDs) or who have contraindications

Methods: In this observational cohort study, patients initiated on tumor necrosis factor inhibitors (TNFi), interleukin-6 inhibitors (IL-6i), abatacept (ABA), or JAKi were included

RESULTS: A total of 31,846 courses were included in the study: 17,522 TNFi, 2,775 ABA, 3,863 IL-6i, and 7,686 JAKi

CONCLUSIONS: JAKi- and IL-6i-adjusted overall discontinuation rates and 1-year remission rates were similar to those observed with TNFi

Source: Lauper K, Iudici M, Mongin D, et al.

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