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OBJECTIVE : Comparing treatment effects in observational settings over time is hindered by several major factors, including confounding and dropout bi.
Objectives : Comparing treatment effects in observational settings over time is hindered by several major factors, including confounding and exit bi.
Methods : PtC was developed using a three-step process according to EULAR standard operating procedur.
Methods Methods : PtC was developed using a three-step process according to EULAR standard operating procedur.
Results Results : Three overarching principles and 10 PtCs were developed , specifically addressing potential biases related to withdrawal or confounding by indicatio.
The three principles include :
- Treatment efficacy is related to how the treatment performs in a routine clinical setting ;
- Inadequacies in observational study data, including confounding and missing data ;
- Well-designed and transparent epidemiological and statistical methods increase confidence in observed data resul.
Conclusions : To improve the reliability of the growing number of real-world comparative validity studies in rheumatology, special attention is needed to reduce potential bi.
CONCLUSIONS CONCLUSIONS : To improve the reliability of the growing number of real-world comparative effectiveness studies in rheumatology, special attention is needed to reduce potential bi.
Courvoisier DS, Lauper K, Kedra J , et a.
EULAR points to consider when analysing and reporting comparative effectiveness research using observational data in rheumatolo.
Annals of the Rheumatic Diseases2022; 81: 780-78 , et al Annals of the Rheumatic Diseases81: Leave a message here
