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    Home > Active Ingredient News > Drugs Articles > APIs rise once an hour, and the company's 24-hour production is not enough to sell, what is the solution to the dilemma of drug discontinuation under the new crown? Industry prediction: we have to wait half a month!

    APIs rise once an hour, and the company's 24-hour production is not enough to sell, what is the solution to the dilemma of drug discontinuation under the new crown? Industry prediction: we have to wait half a month!

    • Last Update: 2022-12-30
    • Source: Internet
    • Author: User
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    After the epidemic was released, Beijingers were busy writing jokes that were false, and buying medicine everywhere was the truth
    .

    After the epidemic was released, Beijingers were busy writing jokes that were false, and buying medicine everywhere was the truth
    .

    "It's been the third year of the epidemic, and I can't buy medicine when it's sealed, why can't I buy it when it's unblocked?" Recently, a Beijing netizen issued such a "soul torture"
    .

    After the epidemic was released, Beijingers were busy writing jokes that were false, and buying medicine everywhere was the truth
    .
    At the same time, the manager of E drug recently learned that some local hospitals are stepping up the "emergency action" of "building a fever clinic in three days and building an ICU in ten days" to cope with the peak period of infection that may be
    faced.

    With some puzzles and questions about these phenomena, E drug managers recently interviewed a number of industry insiders to try to find out the reasons behind the phenomenon and the solution
    .

    01 "It's hard to avoid in a short time"

    01 "It's hard to avoid in a short time"

    "In the past, it was lockdowns such as buying vegetables, but now it is buying medicine and other fevers
    .
    " A paragraph from the capital is actually full of key reasons why
    the next medicine is difficult to find.

    "After three years of the epidemic, our pharmaceutical resource capacity and reserves should be sufficient
    .
    However, with the rapid change of policy, it is difficult to avoid the phenomenon of large-scale rush purchases and runs on medical resources in a short period of time
    .
    Cai Jiangnan, executive director of Shanghai Chuangqi Health Development Research Institute, said
    in an interview with E drug managers.
    The supply of medicines is quantified, and there should be no problem
    with normal operation.
    If there are no infected people to rush to buy "waiting for the yang", no amount of reserves is enough to support this demand
    .
    There will inevitably be a phenomenon
    that "people who stock medicine wait for yang, and people who are yang can't buy medicine".

    After three years of the epidemic, our medical resource production capacity and reserves should be sufficient
    .
    However, with the rapid change of policy, it is difficult to avoid the phenomenon of large-scale rush purchases and runs on medical resources in a short period of time
    .

    Taking ibuprofen as an example, according to public information, China is the world's largest producer and exporter of ibuprofen, accounting for one-third
    of the global production capacity.
    85% of production in China in 2020 Ibuprofen APIs are used for export
    .
    There are also many downstream preparation manufacturers, and searching for ibuprofen as a keyword on the website of the State Food and Drug Administration can obtain a total of 558 approval numbers, involving hundreds of manufacturers
    .

    According to such a production volume, there should be no problem
    in ensuring normal operation of drug supply.
    "But the strict prevention and control and propaganda adopted before made it impossible for the people to stop panic in an instant
    .
    " Cai Jiangnan pointed out, "The government should mobilize more experts, scientists, and doctors to do some popular science publicity as soon as possible, and through various media means, so that the people can stabilize.
    "

    "In addition to the lack of psychological preparation of the people and the rush to buy and hoard drugs caused by panic, the previous policy continued to restrict the sales of four types of drugs, resulting in
    insufficient reserves in pharmacies and hospitals, and one of the important reasons for the phenomenon that one drug is difficult to find.
    " Xu Yucai, former deputy director of the Shanyang County Health Bureau in Shaanxi Province, pointed out
    in an interview with E drug managers.

    In addition to the lack of psychological preparation of the people and the rush to buy and hoard drugs caused by panic, the previous policy continued to restrict the sales of four types of drugs, resulting in
    insufficient reserves in pharmacies and hospitals, and one of the important reasons for the phenomenon that one drug is difficult to find.

    In the past three years of epidemic prevention and control, the government has implemented strict control over the sales of cough, antipyretic, antiviral and antibiotic drugs, which is obvious to all
    .
    And for pharmacies, the drug itself has a shelf life, and it is impossible to reserve
    a large amount for a long time.
    At present, it is difficult to support demand when encountering such centralized
    purchases.
    The shortage of medicines, in turn, has suddenly increased people's anxiety under the epidemic
    .
    The superposition of the two is the crux of the current "one medicine is difficult to find"
    .

    At the same time, Xu Yucai believes that in terms of traditional Chinese medicine, we should not only focus on Chinese proprietary medicine, but should see the value of "drinking tablets" and decoctions, which can solve big problems
    .

    Although the difficulty of buying medicine is a short-term necessity, there are also ways
    to alleviate it.
    "In addition to strengthening correct guidance, in response to this short-term phenomenon, the government can allocate from places with more resources to places with less resources," Cai Jiangnan pointed out.

    Just recently, the State Administration for Market Regulation publicly disclosed a number of typical cases such as "Beijing Yuantong People's Ping An Pharmacy Co.
    , Ltd.
    significantly increased the price of price gouging", "Beijing Rehabilitation Home Medical Supplies Co.
    , Ltd.
    Chaoyang First Branch significantly increased the price of price gouging" and other typical cases
    .

    It is also necessary to deal with
    some violations of law and discipline and disruption of the market.

    02"When will normal supplies be restored?" ”

    02"When will normal supplies be restored?" ”

    According to an industry insider familiar with the production of ibuprofen, it is necessary to wait at least until 15 to 20 if you want ibuprofen to no longer be in short supply Diva
    .
    Because the demand for ibuprofen was not large, the relevant production capacity was put on hold, and after the demand blowout, many companies have just resumed production of ibuprofen, and it is expected that the time for the product to return to the market will be in mid-to-late December
    .

    The manager of E medicine learned from Sichuan Kelun Pharmaceutical Trading Group Co.
    , Ltd.
    that the recent surge in the purchase of drugs from medical institutions and pharmacies in Sichuan has reached more than 3 times the level in the same period, and the daily sales of Kelun Pharmacy have increased by more than 5 times year-on-year.

    Recently, the purchase of drugs from medical institutions and pharmacies in Sichuan has surged, reaching more than 3 times the level in the same period, and the daily sales of Kelun Pharmacy have increased by more than 5 times year-on-year

    At present, the company is fully responding to the government's requirements for strengthening drug reserves and stabilizing prices and guaranteeing supply, coordinating more than 5,000 pharmaceutical manufacturers to increase the release of pharmaceutical and medical products in Sichuan, and continuously increasing the supply of
    cold fever-reducing drugs, new coronavirus detection antigens, N95 masks and other pharmaceutical and medical materials.
    In the past month, more than 1 billion yuan of drugs have been invested in nearly 40,000 hospitals, pharmacies, clinics, etc.
    in Sichuan, with more than 8 million new crown antigen detection reagents and 20 million
    masks alone.

    As an early relaxation of epidemic prevention and control, Guangzhou has also encountered the problem
    of tight supply.
    The lifting of the epidemic lockdown and the peak sales season of traditional cold medicines have expanded people's demand for proprietary Chinese medicines to fight viral colds.

    Guangzhou Xiangxue Pharmaceutical Co.
    , Ltd.
    said that the company's main antiviral oral liquid sales increased by 3-5 times compared with usual, in order to meet the market and the public's drug demand, has expanded two production lines to increase production capacity, factory production workshop to start the "three-shift system" 24-hour overtime production and continue to increase the supply and procurement
    of medicinal materials, packaging materials, etc.
    Even the quality department is sending more inspectors to work overtime to ensure that the increase in production does not degrade
    .

    However, there is also an industry analyst who disclosed information that attracted the attention of E drug managers: "Now the APIs of some drugs are rising, even one price
    per hour.
    " ”

    "Now the APIs of some drugs are rising, even one price
    per hour.
    "

    This can't help but remind people of the situation that masks were difficult to find at the beginning of the epidemic, and at that time it also limited the final sales of masks and did not allow price increases, but raw materials such as non-woven fabrics soared
    .
    As a result, for a period of time, many mask manufacturers can only "lose money for epidemic prevention" or simply stop production
    .
    The original policy requirements to ensure that the people buy at affordable prices have exacerbated the problem of
    insufficient supply.

    The industry insider hopes that this phenomenon in the field of APIs can attract the attention
    of relevant departments.
    Otherwise, it is easy to affect the production enthusiasm
    of the enterprise.
    Just recently, Northeast Pharmaceutical was fined 133 million yuan by the Liaoning Provincial Administration for Market Regulation for abusing the dominant market position of L-carnitine APIs
    .
    Some insiders speculate that the regulatory authorities at this time punished the incident in which Northeast Pharmaceutical was registered in 2019, or there was a certain warning for the now hot antipyretic drugs such as ibuprofen and acetaminophen
    .

    03 The way to alleviation: social forces must be activated

    03 The way to alleviation: social forces must be activated

    On the day of the interview with the manager of E Pharmaceutical, a colleague had just purchased oral small molecule new coronavirus treatment Azvudine tablets
    through online channels.
    "Just place an order through the mini program, submit a self-test antigen that shows positive, pass the prescription review, and an online prescription will be issued and paid
    online.
    " She said
    .
    However, the whole process did not see the relevant way
    to pay through medical insurance.

    The manager of E Pharma also learned from Real Bio that Real Bio has a modern production base in Pingdingshan, which successfully passed the GMP compliance inspection in May 2022, achieving an annual production capacity of more than 3 billion tablets, and is making every effort to ensure drug supply reserves
    .

    "In the epidemic, Internet medical care has played an important role
    .
    Especially at the beginning, many hospitals could not accept offline consultations, and a large number of patients solved their urgent needs
    through online consultation and drug dispensing.
    Cai Jiangnan pointed out, "Recently, the government has also emphasized that after the policy shift, it is necessary to play a good role in Internet medical care, which is some good changes
    .
    " ”

    But at the same time, he also pointed out that in the past year or two, many public hospitals and large tertiary hospitals have established their own Internet hospitals
    .
    The Internet medical treatment promoted by "administrative arrangements" often does not have enough resources, funds and technical support, and there are congenital deficiencies
    .
    In order to truly release the role of Internet medical care in the medical system and better serve the people's medical treatment, it is still necessary to continue to loosen the system in areas such as medical insurance payment, so that enterprises and the market can exert greater energy
    .

    In order to truly release the role of Internet medical care in the medical system and better serve the people's medical treatment, it is still necessary to continue to loosen the system in areas such as medical insurance payment, so that enterprises and the market can exert greater energy
    .

    "If the epidemic control is relaxed, we will have to rely on ourselves in the future
    .
    " For OTC drugs, this is not a joke, let alone an empty phrase
    .
    "This problem involves not only the difficulty of buying drugs during the current epidemic, but also the shortage of medical resources after the arrival of aging in the future
    .
    " An industry expert of OTC drugs pointed out that from the current point of view, a lot of policy attention is still put more resources on the medical side and the treatment field, rather than in the public's self-medication, self-care, self-health field
    .
    Increasing the attention to the latter and increasing the scientific publicity of OTC drugs play a very important role
    in alleviating the tension between supply and demand of medical resources.

    In addition to the difficulty of buying medicine, after the policy is liberalized, the problem of difficulty in seeing a doctor is also thought-provoking
    .
    Xu Yucai once wrote that the most important thing at present is to recommend that the state adjust the "Class B A pipe" as soon as possible, otherwise it will be difficult for grassroots hospitals to carry out the work and face legal risks
    .

    Xu Yucai quoted Hu Xiaoxiang, vice president of the Jiangsu Health Law Society, as saying in the article that since the new crown is still "Class B tube", such as a doctor Yang, can he continue to "face guests"? A "tube A" infectious disease is certainly not legally possible
    .
    Once complained by a patient, or complained by the employee, or merged by the employee and complained by the patient he contacted, the hospital is closed
    .
    Especially if there is a persistent infection, criminal liability
    is not even excluded.

    At the same time, in his view, the current policy has not mobilized all the medical resources of society
    .
    "You can't just look at public healthcare
    .
    Clinics, pharmacies, village clinics, etc.
    should be fully liberalized to provide services, and everyone should not be allowed to go to fever clinics
    .
    Otherwise
    , it is difficult to avoid a run on medical resources.
    Xu Yucai said bluntly, "From the current point of view, our years of graded diagnosis and treatment have not made substantial achievements
    .

    In his view
    , the current policy has not mobilized all the medical resources of society.

    Cai Jiangnan also pointed out this problem
    .
    "We must fully develop socialized medical services, and the proportion of public medical care will decline
    .
    " Let public medical care and private medical care form a healthy competition and promote
    each other.
    Cai Jiangnan believes that "only by full competition can we find the market price of medical services, and can there be a mechanism for consultation and negotiation between medical institutions and the government, rather than directly setting the price to death
    .
    " If this is not solved, it will be difficult for graded diagnosis and treatment to be truly implemented, and it will be difficult for social medical resources to be fully mobilized
    .

    Just today, Zhang Chaoyang, the founder of Sohu, also "yang" passed, and posted that "only two ibuprofen were consumed, a box of ibuprofen 24 capsules, enough for several people" called on everyone not to hoard fever-reducing medicine, but to let the elderly and people who have no money and resources have fever-reducing medicine
    .
    It is believed that with the change in people's perception of the new crown virus, the situation that one drug is difficult to find will soon be alleviated
    .
    But I wonder how much time it will take to solve the protracted dilemma of graded diagnosis and treatment and the difficulty of medical supply and demand?

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