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▎Editor of WuXi AppTec's content team Alzheimer's disease is the type of dementia with the highest incidence in the world
.
The "Guidelines for the Primary Prevention of Alzheimer's Disease in China" pointed out that the prevalence of Alzheimer's disease among people over 65 years old in China is between 3% and 4%
.
In other words, 3 to 4 out of every 100 Chinese elderly people currently suffer from this disease
.
By 2050, China's Alzheimer's disease patients are expected to reach 21 million
.
The "China Development Report 2020: Development Trends and Policies of China's Population Aging" predicts that by 2050, about 5 out of every 100 people over 65 will have Alzheimer's disease
.
As the aging trend accelerates, Alzheimer’s disease is the most common neurodegenerative disease among the elderly.
People hope that this disease can be prevented in a better and more timely manner, so that more people can understand its early symptoms, Raising vigilance is very important
.
In recent decades, people have noticed that many psychological problems are also related to cognitive decline and Alzheimer's disease, such as anxiety and depression
.
A recent study showed that late middle age (51-60 years old in this study) symptoms of depression and anxiety may be an indicator of Alzheimer's disease progression in the earliest stages
.
Why do you think of linking anxiety and depression with this disease? Image source: Creative Commons CC0 1.
0, Universal Public Domain Dedication, via wikipedia commons, author: geralt Because researchers have found that depression and anxiety symptoms may increase the risk of cognitive decline, and cognitive decline is an early sign of dementia
.
If we can further understand the relationship between these mental illnesses and middle-aged cognitive ability, perhaps more people at risk of dementia can be screened out and intervention and treatment can be carried out earlier
.
In order to verify the above conclusions, the research team recruited 2657 community residents aged 40 to 70 to participate in the study
.
They do not have any dementia or related cognitive impairment problems, nor do they have serious brain trauma, nervous system or mental illness, and they have never used any drugs to treat Alzheimer's disease
.
This research was led by the Monash University, Turner Institute for Brain and Mental Health in Australia.
The research used a variety of methods to measure depression and anxiety, hoping to measure it as accurately as possible The two dimensions of the structure of mental illness; the measurement of objective cognition uses the neuropsychological scale (Cogstate); the evaluation of subjective cognition uses the Alzheimer's Disease Cooperative Study (ADCS) Cognitive Function Inventory (CFI)
.
In the depression scale of the research and test, it was found that there are 5 symptom factors that may have an impact on the cognitive level (memory, attention) and the comprehensive score of cognitive function: indifference, fatigue, negative emotions, positive emotions and low self-esteem
.
The Anxiety Scale found three factors that affect cognition: nervousness, panic, and physical symptoms
.
Picture source: 123RF Finally, the study came to the following conclusions: 1) Generally speaking, compared with people without mental illness, there is a higher level of anxiety symptoms (rather than depression symptoms) in the late middle age (51-60 years old) ), the concentration and memory may be worse
.
2) People aged 51-60 with higher levels of anxiety symptoms, especially those with higher levels of "physical fatigue" symptoms, are more subjectively concerned about their cognitive decline
.
3) In the 61-70-year-old age group, the effect of increasing age on memory decline is greater than that of depression and anxiety symptoms
.
4) In the 40-50 year-old age group, regardless of the severity of depression and anxiety symptoms, no relevant differences were found in the level of memory
.
"The results of the study show that they are subjectively worried about their own cognitive level, which may be related to psychological or emotional symptoms, but they do not really have memory or thinking dysfunction, at least in the middle-aged population
.
" Associate Professor Yen Ying Lim, one of the authors of the study, said
.
Image source: Creative Commons CC0 1.
0, Universal Public Domain Dedication, via wikipedia commons, author: https://pixabay.
com/users/pasja1000-6355831/ Anxiety symptoms in middle age may increase the risk of dementia in later life, and screening Checking these symptoms can help identify people who are at risk of cognitive decline and help us prevent dementia more effectively
.
As Associate Professor Yen Ying Lim summarized, “What is going on in the brain? From depression and anxiety symptoms, cognitive decline, and finally to dementia, how did it develop step by step? To know the exact answer, we need more in the future.
Research
.
"So, how to prevent depression and anxiety? The work pressure and pace of life in modern society make negative emotions such as anxiety and depression high in the population.
After the outbreak of the new crown epidemic, the proportion of anxiety and depression is also in some groups.
As it rises, mental health and mood have become more and more important issues that cannot be ignored
.
Studies have pointed out that: exercise will provide a kind of individualized therapy with few side effects and easy to start.
It can be used alone or in combination with other standard therapies to help people to a certain extent.
Relieve anxiety
.
Image source: 123RF.
In addition, studies have shown that meditation can relieve daily stress, reduce anxiety and depression-related emotional symptoms, prevent cardiovascular disease, and improve overall emotional state and well-being
.
It is recommended to read 34-year-old graduate student's sudden death in the middle of the night: These 2 habits, early understanding may save your life.
Sudden death of a 79-year-old man moving express delivery: This action is particularly fatal to 3 types of people.
Harvard study of more than 200,000 people: The more 4 types of food you eat, The easier it is to find cancer in the world's longest-lived place, in China! With these 3 points, it is hard not to live long! Alzheimer's disease in your 30s? The memory is so bad that you really need to be vigilant! References[1] Anxiety symptoms may be early indicator of Alzheimer's disease.
Retrieved Nov 26, 2021, from https://medicalxpress.
com/news/2021-11-anxiety-symptoms-early-indicator-alzheimer.
html[2] Stephanie Perin, et al.
, (2021).
Elucidating the association between depression, anxiety, and cognition in middle-aged adults: Application of dimensional and categorical approaches.
Journal of Affective Disorders, DOI: 10.
1016/j.
jad.
2021.
10.
007 Note: This article aims to introduce the progress of medical and health research, not to recommend treatment options
.
If you need guidance on the treatment plan, please go to a regular hospital for treatment
.
.
The "Guidelines for the Primary Prevention of Alzheimer's Disease in China" pointed out that the prevalence of Alzheimer's disease among people over 65 years old in China is between 3% and 4%
.
In other words, 3 to 4 out of every 100 Chinese elderly people currently suffer from this disease
.
By 2050, China's Alzheimer's disease patients are expected to reach 21 million
.
The "China Development Report 2020: Development Trends and Policies of China's Population Aging" predicts that by 2050, about 5 out of every 100 people over 65 will have Alzheimer's disease
.
As the aging trend accelerates, Alzheimer’s disease is the most common neurodegenerative disease among the elderly.
People hope that this disease can be prevented in a better and more timely manner, so that more people can understand its early symptoms, Raising vigilance is very important
.
In recent decades, people have noticed that many psychological problems are also related to cognitive decline and Alzheimer's disease, such as anxiety and depression
.
A recent study showed that late middle age (51-60 years old in this study) symptoms of depression and anxiety may be an indicator of Alzheimer's disease progression in the earliest stages
.
Why do you think of linking anxiety and depression with this disease? Image source: Creative Commons CC0 1.
0, Universal Public Domain Dedication, via wikipedia commons, author: geralt Because researchers have found that depression and anxiety symptoms may increase the risk of cognitive decline, and cognitive decline is an early sign of dementia
.
If we can further understand the relationship between these mental illnesses and middle-aged cognitive ability, perhaps more people at risk of dementia can be screened out and intervention and treatment can be carried out earlier
.
In order to verify the above conclusions, the research team recruited 2657 community residents aged 40 to 70 to participate in the study
.
They do not have any dementia or related cognitive impairment problems, nor do they have serious brain trauma, nervous system or mental illness, and they have never used any drugs to treat Alzheimer's disease
.
This research was led by the Monash University, Turner Institute for Brain and Mental Health in Australia.
The research used a variety of methods to measure depression and anxiety, hoping to measure it as accurately as possible The two dimensions of the structure of mental illness; the measurement of objective cognition uses the neuropsychological scale (Cogstate); the evaluation of subjective cognition uses the Alzheimer's Disease Cooperative Study (ADCS) Cognitive Function Inventory (CFI)
.
In the depression scale of the research and test, it was found that there are 5 symptom factors that may have an impact on the cognitive level (memory, attention) and the comprehensive score of cognitive function: indifference, fatigue, negative emotions, positive emotions and low self-esteem
.
The Anxiety Scale found three factors that affect cognition: nervousness, panic, and physical symptoms
.
Picture source: 123RF Finally, the study came to the following conclusions: 1) Generally speaking, compared with people without mental illness, there is a higher level of anxiety symptoms (rather than depression symptoms) in the late middle age (51-60 years old) ), the concentration and memory may be worse
.
2) People aged 51-60 with higher levels of anxiety symptoms, especially those with higher levels of "physical fatigue" symptoms, are more subjectively concerned about their cognitive decline
.
3) In the 61-70-year-old age group, the effect of increasing age on memory decline is greater than that of depression and anxiety symptoms
.
4) In the 40-50 year-old age group, regardless of the severity of depression and anxiety symptoms, no relevant differences were found in the level of memory
.
"The results of the study show that they are subjectively worried about their own cognitive level, which may be related to psychological or emotional symptoms, but they do not really have memory or thinking dysfunction, at least in the middle-aged population
.
" Associate Professor Yen Ying Lim, one of the authors of the study, said
.
Image source: Creative Commons CC0 1.
0, Universal Public Domain Dedication, via wikipedia commons, author: https://pixabay.
com/users/pasja1000-6355831/ Anxiety symptoms in middle age may increase the risk of dementia in later life, and screening Checking these symptoms can help identify people who are at risk of cognitive decline and help us prevent dementia more effectively
.
As Associate Professor Yen Ying Lim summarized, “What is going on in the brain? From depression and anxiety symptoms, cognitive decline, and finally to dementia, how did it develop step by step? To know the exact answer, we need more in the future.
Research
.
"So, how to prevent depression and anxiety? The work pressure and pace of life in modern society make negative emotions such as anxiety and depression high in the population.
After the outbreak of the new crown epidemic, the proportion of anxiety and depression is also in some groups.
As it rises, mental health and mood have become more and more important issues that cannot be ignored
.
Studies have pointed out that: exercise will provide a kind of individualized therapy with few side effects and easy to start.
It can be used alone or in combination with other standard therapies to help people to a certain extent.
Relieve anxiety
.
Image source: 123RF.
In addition, studies have shown that meditation can relieve daily stress, reduce anxiety and depression-related emotional symptoms, prevent cardiovascular disease, and improve overall emotional state and well-being
.
It is recommended to read 34-year-old graduate student's sudden death in the middle of the night: These 2 habits, early understanding may save your life.
Sudden death of a 79-year-old man moving express delivery: This action is particularly fatal to 3 types of people.
Harvard study of more than 200,000 people: The more 4 types of food you eat, The easier it is to find cancer in the world's longest-lived place, in China! With these 3 points, it is hard not to live long! Alzheimer's disease in your 30s? The memory is so bad that you really need to be vigilant! References[1] Anxiety symptoms may be early indicator of Alzheimer's disease.
Retrieved Nov 26, 2021, from https://medicalxpress.
com/news/2021-11-anxiety-symptoms-early-indicator-alzheimer.
html[2] Stephanie Perin, et al.
, (2021).
Elucidating the association between depression, anxiety, and cognition in middle-aged adults: Application of dimensional and categorical approaches.
Journal of Affective Disorders, DOI: 10.
1016/j.
jad.
2021.
10.
007 Note: This article aims to introduce the progress of medical and health research, not to recommend treatment options
.
If you need guidance on the treatment plan, please go to a regular hospital for treatment
.
