Antioxidation of natural carotene

According to the report, Dunaliella salina extract (rich in natural carotene) can reduce the level of lipid peroxidation in mice blood and liver tissue, and increase the activity of antioxidant enzymes in blood or liver tissue 1 mg / kg body weight of natural carotene or 1.25, 0.63 and 0.31 mg / kg body weight of alginate extract were given orally for 30 days The results showed that malondialdehyde (MDA) in the blood and liver tissue of mice in each administration group was significantly lower than that in the control group, and GSH PX activity in the blood and liver tissue of mice in the natural carotene group and the high and medium dose groups of Dunaliella salina extract was significantly higher than that in the control group; SOD activity in the liver tissue of mice in each administration group was significantly higher than that in the control group It has been reported that the MDA level in the liver tissue of rats and mice treated with extract concentrate (rich in natural carotene) decreased while the SOD activity increased Rats and mice were given the preparation orally at doses of 5, 35, 70 mg / kg body weight and 20, 50, 100 mg / kg body weight for 10 days The results showed that the MDA level in liver tissue of rats in middle and high dose group and mice in each dose group decreased significantly, while the SOD activity increased significantly ◆ enhance the anti-oxidation function of tumor patients According to the research, the MDA level in the blood of tumor patients after oral administration of Dunaliella salina extract (natural carotene) decreased, GSH PX and SOD activity increased 44 tumor patients (15 lung cancer, 8 malignant lymphoma, 6 gastric cancer, 4 colorectal cancer, 3 esophageal cancer, 2 breast cancer, 2 thyroid cancer, 2 liposarcoma, 1 nasopharyngeal cancer, 1 ovarian cancer) were treated with salina extract orally 30 mg salina extract was orally taken twice a day for one month In addition, 15 cases in the control group had the same disease type and severity as those in the oral extract group The results showed that the MDA level in the blood was significantly lower after taking the extract than before, and the GSH PX and SOD activities were significantly higher than before taking the extract ◆ enhance the antioxidant capacity of children exposed to radiation in the Chernobyl nuclear leakage event According to the research, the serum analysis of children who migrated from Russia to Israel after the Chernobyl nuclear leakage event (1990-1994) found that the level of oxidative conjugated diene increased, indicating that the formation of lipid peroxidation in children from the radiation pollution area increased Among them, 57 boys and 42 girls were orally given Dunaliella salina powder (9-cis and full trans equivalent mixture of natural carotene) rich in natural carotene for 3 months The results showed that the level of serum oxidative conjugated diene in children taking natural carotene was significantly lower than that before taking natural carotene, indicating that natural carotene can be used as antioxidant or radiation protective agent.