Annals of Neurology: New research helps promote neuronal regeneration.

20, 2020 /--- -- Researchers at the University of Alberta recently found a treatment that can increase nerve regeneration three to five times faster, promising better treatments for trauma surgery patients.
"If the growing nerves don't reach the muscles fast enough, they won't get functional repair," said Christine Webber, an associate professor in the Department of Anatomy at American University and a member of the Institute of Neuroscience and Mental Health.
"about two-thirds of trauma patients have peripheral nerve damage."
of nerve regeneration means that muscles usually atrophy before nerves grow and reconnect.
(Photo: www.pixabay.com) and regulating electrical stimulation (CES) have a positive impact on this.
Weber et al. have previously conducted in-depth research on CES.
stimulate nerves for 1 hour by electrically stimulating them at a fairly low frequency, and neurosurgery was performed a week after CES treatment.
nerve regeneration was three to five times faster than in the control group that did not have CES.
new study, Webber et al. have developed a model of a nerve-damaged animal called "foot drooping."
is a common injury that hinders a patient's ability to walk normally and affects his or her quality of life.
, the only treatment for the disease was to affect the patient's gait through surgery or orthotics.
Weber et al. first performed far-end nerve transfer in this study, using electrical stimulation to activate nerve cells near damaged nerves.
week after the attack, a branch of the nerve is cut open and placed near the target of the ins functional nerve.
, the newly transferred nerves are infused and ready to enter the foot muscles at a faster rate.
CES can be a tool for faster regeneration of nerves in any part of the peripheral nervous system.
, who is also a member of the Institute of Neuroscience and Mental Health, has begun a clinical trial involving the use of CES before nerve repair in the wrist tube.
hopes that in the next year or two, we will be able to use the information obtained by examining nerve transfer in the legs, which can become a difficult part of the body for nerve regeneration because of the large area that the nerves must cover.
(bioon.com) Source: Researchers find way to speed up nerve regrowth for trauma patients Source: Jenna-Lynn B. Senger et al, Conditioning Services Developments Design in Nerve Transfers, Annals of Neurology (2020). DOI: 10.1002/ana.25796.