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Ann Rheum Dis: The use of vitamin K antagonists is associated with an increased risk of the onset and progression of osteoarthritis

 Last Update: 2021-04-23
 Source: Internet
 Author: User

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Assuming that vitamin K plays a role in the pathogenesis of osteoarthritis (OA) by affecting vitamin K-dependent bone and cartilage proteins, vitamin K may be a modifiable risk factor.

Among the 3494 participants in the Rotterdam study cohort, the effect of the new anticoagulation on the incidence and progression of OA was studied.

The use of new anticoagulation was associated with an increased risk of OA and progression (OR=2.

The use of new anticoagulation and the risk of OA

Thus, these findings support the importance of vitamin K and vitamin K-dependent proteins (such as MGP) in the pathogenesis of OA.

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Original source: Original source:

Cindy G Boer.

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