Ann Rheum Dis: Is the epidemiology of rheumatoid arthritis changing? Results of the study on population morbidity, 1985-2014

The study was designed to explore trends in the incidence of rheumatoid arthritis (
RA) in2015-
compared withand1985-1994researchers assess edgto trends inRAin a population-based initial queue thatincludes18years of agethe18-year-old sage11,
101-11,
-1,-1, 2014,-
-11,
The incidence was estimated and adjusted for age and gender based on white Americans in2010The incidence trend was analyzed using thePoissonregression methodincidence cohort foryears 2005-2014 included 427 patients: average age 55.4 years old, 68 % of women, RF positive 51 %, anticyclic lysine antibody positive 50 % 2005-2014 , the overall annual incidence rate of RA adjusted by age and gender was 41/100,000 (age-adjusted incidence rate: 53/100,000 for women and 2 9/100000 for men) Although these estimates are similar to those of 1995-2004, the incidence of RF -positive RA decreased in 2005-2014 compared to the previous (
p-0.004 ) and the incidence of RF -negative cases (
p 0.001 ) From early age to recent years, smoking rates have declined and obesity rates have risen use the 1987 ACR standard, the incidence of RF -negative RA increased significantly from 2005 to 2014 to 2014 compared to the previous , while the incidence of RF -positive RA decreased the overall incidence of RA in 2005-2014 is similar to that of the previous 10,
years Changes in the prevalence of environmental factors, such as smoking and obesity, may lead to these trends Whether these trends represent changes in RA serological characteristics still requires further investigation