Anhui Anke injection recombined human growth hormone new adaptive disease listing application is to be included in the priority review

Anhui Anke's recombined human growth hormone has been approved at home and abroad for the treatment of a variety of children's short body-related adaptive disorders, this application for increased ISS adaptives has been approved in the United States.
At present, the domestic market has not been approved, but the use of growth hormone for the treatment of idiotic dwarfs has been included in the Chinese medical science journal "Short body children's diagnosis and treatment guide" and "Idiotic short children's diagnosis and treatment consensus statement" and other industry guidelines.
injection recombination human growth hormone (commodity name: Ansu Meng) has been approved for listing in China 6 adaptive disorders: 1) for children due to endogenous growth hormone deficiency caused by slow growth; 2) for children due to Noonan syndrome caused by short stature 3) For children with short stature or growth disorders caused by SHOX gene defects; 4) for severe burns treatment; 5) for children with short stature caused by cartilage developmental insemination; and 6) for adult short intestine syndrome, which is supported by nutrition.
this new adaptation is a rich and complementary to approved adaptive disorders, which, if approved, will help to address the clinical drug needs of such children.
short body refers to the similar living environment, the individual height is lower than the same race, the same age, the same sex normal population 3 percentile or lower than the average height of the normal population 2 standard deviation (-2SD).
According to statistics, the occurrence rate of children's short stature in China is about 3%, and idepathic dwarf is the most common type of children's short stature, refers to no systemic, endocrine, nutritional diseases or chromosomal abnormality of small stature, ISS children's birth weight and growth hormone water level is normal, ISS can be caused by a variety of currently unclear causes, accounting for about 60%-80% of all small children.
children's short stature not only brings serious harm to children's physical and mental health, interpersonal communication, social employment, etc., but also brings heavy burden to society.