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Recent infection with monkeypox virus may initially present with few obvious clinical signs and absence of signs of infection, with only a few skin vesicles visible
.
Stefan Schlabe and his collaborators presented the case of a 51-year-old HIV-positive patient whose mouth ulcer was the first sign of monkeypox virus infection (Schlabe S, Isselstein J, Boesecke C: Mouth ulcer is the first sign of monkeypox virus infection).
Dtsch Arztebl Int 2022; 119: 511
。 DOI: 10.
3238 / arztebl.
m2022.
0274)
。
The patient proposed to his GP that there was a vesicle
in the corner of the left mouth, which appeared the day before.
He has no clinical signs of infection; Over the years, his HIV infection has been well controlled
virologically and immunologically through antiretroviral therapy.
Initially, the patient's ulcer is treated
with a local combined ointment.
A few days later, he developed a painful ulcer in the corner of his left mouth and went to his GP
again.
A cotton swab
was taken from the ulcer.
Polymerase chain reaction (PCR) test confirmed monkeypox virus
.
Subsequently, an increase in monkeypox vesicles was noted on the skin, also on the
palate.
As the base of the tongue became increasingly swollen and speech slurred, doctors decided to hospitalize the patient for antiviral treatment
with tecovirrimat.
