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On April 22, Chen Peng and Zou Peng from the Life Center, School of Chemistry and Molecular Engineering, Peking University, and Fan Xinyuan, School of Chemistry and Molecular Engineering, Peking University jointly published a paper entitled "Photocatalytic Chemical Crosslinking for Profiling RNA- "Protein Interactions in Living Cells" research paper
In order to solve the above problems, the authors are committed to developing a low toxicity, high efficiency, and broad application to various samples of RNA-binding protein analysis strategy
Overall, by designing bifunctional probes reactive with both RNA and protein, the method has higher labeling efficiency, biocompatibility, and generality than previously reported methods, which can be applied to tissue samples analysis