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    Home > Active Ingredient News > Anesthesia Topics > Anesthesiology: Olanzapine can effectively reduce the risk of vomiting after discharge from ambulatory surgery

    Anesthesiology: Olanzapine can effectively reduce the risk of vomiting after discharge from ambulatory surgery

    • Last Update: 2021-03-17
    • Source: Internet
    • Author: User
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    Nausea and vomiting after discharge from hospital after ambulatory surgery is a common problem, and there is still no good solution.


    The study included 140 adult female patients 50 years of age or younger who underwent ambulatory gynecological or plastic surgery under general anesthesia.


     

    The results showed that the main outcome occurred in 26 patients (38%) in the placebo group and 10 patients (14%) in the olanzapine group (RR, 0.


    Table 1.


    In summary, the results of the study show that when combined with ondansetron and dexamethasone, olanzapine reduces the risk of nausea and/or vomiting within 24 hours after discharge from ambulatory surgery patients compared to placebo, and reduces It was about 60%, but the sedation score increased slightly.


     

    Original source:

     

    Jaime B Hyman, Chang Park, et al.


    ncbi.
    nlm.
    nih.
    gov/32229754/" target="_blank" rel="noopener">Olanzapine for the Prevention of Postdischarge Nausea and Vomiting after Ambulatory Surgery: A Randomized Controlled Trial in this message
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