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background
backgroundEpidural local anesthetics mainly act on the epidural nerve roots and can directly act on the spinal cord through the dura mater
.
We hypothesized that epidural administration of ropivacaine would reduce the amplitude of transcranial motor evoked potentials by blocking spinal nerve conduction
method
methodAccording to the epidural concentration of ropivacaine, 30 adult patients undergoing lung surgery were randomly divided into 3 groups: 0.
2% group, 0.
375% group and 0.
75% group
.
The blinding method is implemented as follows: the attending anesthesiologist, the doctor in charge of neurophysiological monitoring and the patient do not know the corresponding group
result
resultThe data are expressed as median (interquartile range)
.
60 minutes after epidural injection of ropivacaine, the 0.
in conclusion
in conclusionCompared with the low-dose group, epidural administration of high concentrations of ropivacaine reduced the amplitude of motor evoked potentials and prolonged the onset latency of motor evoked potentials and SSEPs
.
High concentrations of ropivacaine can act on the motor pathways through the dura mater
Original source:
Original source:Kenta Furutani, Toshiyuki Tobita, Hideaki Ishii, et al.
Epidural Administration of Ropivacaine Reduces the Amplitude of Transcranial Electrical Motor-Evoked Potentials: A Double-Blinded, Randomized, Controlled Trial in this message
