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Antioxidant nutrients such as polyphenols in pomegranate juice can prevent damage to neurons from free fundamentals produced during normal metabolism.
Previous studies in animals and short-term clinical trial results in middle-aged and older adults support the potential memory benefits of pomegranate juice;
a recent clinical trial that looked at the long-term effects of pomegranate juice on the memory of dementia-free middle-aged and older adults, was published online online in The American Journal of Clinical Nutrition.
In this 12-month randomized double-blind placebo-controlled trial, we included 210 subjects (aged 50-75 y) who were randomly assigned to ingest pomegranate juice (8 ounces (236.5 mL) per day) or placebo drinks (8 ounces, in addition to pomegranate polyphenols, which match the ingredients of pomegranate juice).
the evaluation of memory measurements at 6 and 12 months (Brief Visual Spatial Memory Test-Revision (BVMT-R) and Buschke Selective Memory Test (SRT) and analyzed using a general linear model of mixed effects.
28 subjects in the pomegranate juice group and 33 subjects in the placebo group withdrew before completing the study.
the baseline variables of 98 pomegranate juice groups and 102 placebo group subjects who completed the study were not significantly different.
for BVMT-R learning, grouping by time interaction is statistically significant (F s2,257 s 5.90, P s 0.003; intergroup effect size There was no significant change in the pomegranate juice group (ES=0.15), while there was a significant decrease in the placebo group (ES=-0.35).
BVMT-R scores and changes in SRT metrics between groups were not significantly different between groups.
, the results showed that drinking pomegranate juice daily stabilized the ability to learn visual information for 12 months.
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