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Many people with rheumatoid arthritis (RA) report that certain foods can relieve symptoms.
early studies have shown that food and food ingredients have a positive effect on RA's clinical outcomes, but there is not enough evidence to provide specific dietary recommendations.
food ingredients may interact, but there is a lack of research to assess the combined effects.
we aim to see if an anti-inflammatory diet can reduce disease activity in RA patients.
in this single-blind cross-over trial, 50 RA patients were randomly assigned to an interventiondiet that included a recommended combination of anti-inflammatory foods, or a controlled diet similar to Sweden's general dietary intake for 10 weeks.
participants switched diets after a 4-month flushing period.
deliver food to their homes every week, which is about 50 percent of energy demand.
the rest of the diet and encourage them to eat the same type of food as they are provided during each meal. the main result of
was a change in the disease activity score-red blood cell deposition rate (DAS28-ESR) of 28 joints.
secondary results are changes in the composition of DAS28-ESR (soft and swollen joints, ESR and generally healthy visual simulation scale) and DAS28-C-reactive proteins.
results, in the main analysis, the linear hybrid ANCOVA model was used, including 47 participants who completed the 1-year diet period, and there was no significant difference between the dry expectation and the control period (P - 0.116).
, however, in the uncorrected analysis, the DAS28-ESR of participants who completed both periods decreased significantly in their dry expectations and significantly lower than the control period after the intervention (n s 44; median: 3.05; IQR: 2.41, 3.79; compared to the median: 3.27; IQR: 2.69, 4.28; P.04, Wilcox's Rankon. there is no significant difference between the
components.
in general, the trial showed that the proposed anti-inflammatory diet had a positive effect on disease activity in RA patients.
more research is needed to determine whether this diet can lead to clinically relevant improvements.
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