Am J Clin Nutr: Eating more walnuts doesn't seem to make you smarter, but it may slow you down.

Eating walnuts can counteract two drivers of cognitive decline - oxidative stress and inflammation - but there is currently no clinical data on cognitive effects.
Walnut and Healthy Aging Study is a randomized controlled trial of two centers (Barcelona, Spain; Lomarinda, California) that looked at the cognitive effects of two years of walnut intervention on cognitive health in older adults.
randomly assigned 708 free-living seniors (63-79 years old, 68% female) to a walnut-rich diet (30-60 g/day) with an energy of 15% or a controlled diet (no walnuts).
a baseline and a comprehensive neurocognitiation test in 2 years.
result is the change of global cognitive composite index.
, we performed repeated structural and functional brain MRI examinations on 108 Barcelona participants.
results, a total of 636 participants completed the intervention.
in addition to differences in nutrient intake, participants from Barcelona smoked more and were less educated, with lower scores on baseline neuropsychological tests than those from Lomalinda.
the walnuts are well tolerated and followed.
improved intentional therapy analysis (n - 657) found no global cognitive differences between the two groups, with an average change of -0.072 (95% CI:-0.100,-the walnut diet group). 0.043), the control diet group is -0.086 (95% CI: -0.115, -0.057) (P - 0.491).
post-morse analysis showed significant differences in the Barcelona queue, with the undesced change in the walnut group being -0.037 (95% CI:-0.077, 0.002) and -0.097 (95% CI:-0.137, -0.057) (P-0.040).
results from a subset of participants in Barcelona showed that functional networking was more capable of collecting in the control group's working memory tasks.
, the results of the study showed that walnut supplement supplementation for 2 years had no effect on the cognition of healthy elderly people.
however, post-mortation analysis of the brain's fMRI and site-by-site suggests that walnuts may delay cognitive decline in high-risk sub-groups.
exciting but inconclusive results deserve further investigation, especially for the weak, who are expected to benefit the most.
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