Am J Clin Nutr: Correlation between dairy products and calcium intake and breast cancer risk

At present, breast cancer is the most common malignant tumor in the world and the leading cause of cancer-related deaths in women.

There is hypothesis that dairy products affect the occurrence of breast cancer in contradictory ways.

The purpose of this study was to evaluate the association between specific dairy products and calcium intake and the overall risk of breast cancer, as well as the risk of different subtypes of breast cancer defined by the estrogen receptor (ER) status .

The researchers compiled individual level data of more than 1 million women, followed up for a maximum of 8-20 years, of which 37,861 cases of invasive breast cancer were reported.

Correlation between intake of specific dairy products and breast cancer risk with different characteristics

In general, no clear associations were found between specific dairy products, dietary calcium (from food only) and total calcium (from food and supplements) intake and overall breast cancer risk .

Although each dairy product has zero or very weak negative correlation with overall breast cancer risk, the correlation between yogurt and cheese/ricotta and breast cancer risk is different due to ER status, which is present with ER-negative breast cancer Certain correlation : The aggregate hazard ratio [HR] of daily intake of 60g and above yogurt compared with less than 1g is 0.

The study showed that adult dairy products or calcium intake may not be associated with breast cancer risk, and high intakes of yogurt and cheese/whey cheese are negatively associated with ER-negative breast cancer risk .

Wu You,Huang Ruyi,Wang Molin et al.