Alzheimer’s has signs decades in advance!

Dementia affects about 50 million people worldwide, and this number is expected to increase more than threefold by 2050, especially in low- and middle-income countries.

Dementia affects about 50 million people worldwide, and this number is expected to increase more than threefold by 2050, especially in low- and middle-income countries.

There is currently no cure for this type of dementia, so prevention is particularly important for reducing the global burden of dementia

It is worth noting that dyslipidemia is not included in the list of changeable risk factors

A recent study published in the journal The Lancet Health and Longevity showed that high levels of low-density lipoprotein cholesterol (LDL-C) in middle age are associated with an increased risk of dementia ten years later

DOI: 10.

• <2.
  
  

  At the end of the study follow-up, among patients diagnosed with dementia, the average age at diagnosis was 79.

  
  There is a moderately positive correlation between low-density lipoprotein cholesterol and dementia.
  
  Is there a difference between the blood lipid level in middle age and the blood lipid level in old age and the risk of dementia?

  In order to clarify this problem, the researchers further analyzed and found that for people who were younger than 65 years old (middle-aged) when measuring cholesterol for the first time and were diagnosed with dementia 10 years after measuring cholesterol, LDL cholesterol increased by 1 The adjusted RR for each SD is 1.

  
  For people who were younger than 65 years old (middle-aged) when their cholesterol was measured for the first time and were diagnosed with dementia 10 years after measuring their cholesterol, the adjusted RR for each increase in low-density lipoprotein cholesterol by one SD is 1.
  
  For people whose first measurement of cholesterol is 65 years or older, the correlation between LDL cholesterol and dementia is relatively weak, with an RR of 1.
  
  This shows that compared with high blood lipid levels in old age, the higher the blood lipid level in middle age, the greater the risk of dementia
  .
  

   According to the age at the time of measurement and the follow-up time, the RRs for the diagnosis of dementia for each increase in low-density lipoprotein cholesterol

   According to the age at the time of measurement and the follow-up time, the RRs for the diagnosis of dementia for each increase in low-density lipoprotein cholesterol

  As mentioned above, the NCEP ATPⅢ report of the United States divides LDL-C into 5 levels for the prevention and treatment of dyslipidemia, so the researchers further analyzed the relationship between these 5 levels of LDL-C and dementia
  .
   

  The results of the study found that for people younger than 65 years old and followed up for more than 10 years, people with LDL levels higher than 190 mg/dL were diagnosed with dementia more than 10 years later than people with levels lower than 100 mg/dL.
  The risk is about 60% higher (full adjustment ratio (RR) is 1.
  59)
  .
  

  People with LDL levels higher than 190mg/dL are about 60% more likely to be diagnosed with dementia more than 10 years later than people with levels lower than 100mg/dL (fully adjusted ratio (RR) 1.
  59)
  .
  

  According to the age at the time of measurement and the follow-up time, different types of low-density lipoprotein cholesterol diagnose RR for dementia

  According to the age at the time of measurement and the follow-up time, different types of low-density lipoprotein cholesterol diagnose RR for dementia

  In addition, researchers found that the association between total cholesterol and the incidence of dementia is weak, while there is no consistent association between HDL cholesterol and triglycerides
  .
  This suggests that the association between total cholesterol and dementia is driven by low-density lipoprotein cholesterol
  .
    

  This suggests that the association between total cholesterol and dementia is driven by low-density lipoprotein cholesterol
  .
  

  In summary, the study shows that high levels of low-density lipoprotein cholesterol can increase the risk of dementia and Alzheimer's disease
  .
  Dementia and Alzheimer's disease are both devastating diseases for individuals and their loved ones.
  So far, there is no cure, so active prevention is still the key
  .
  Protecting your memory and thinking starts with maintaining a suitable level of low-density lipoprotein cholesterol!

  Therefore, active prevention is still the key
  .
  Protecting your memory and thinking starts with maintaining a suitable level of low-density lipoprotein cholesterol!
  
  Leave a message here