Alzheimers Dementia: What are the clinical characteristics of dementia patients in a survey of 4 million people?

Alzheimer's disease is a leading cause of death and morbidity in the elderly population worldwide
.

In the UK, dementia has been the most common cause of death for women since 2011 and the second leading cause of death for men since 2015

 

People with dementia are likely to have comorbidities that require additional health care attention in addition to dementia-related illnesses
.

As a result, dementia and a variety of long-term conditions can place a significant burden on patients' health, access to medical services, and social care services

Dementia is defined as a decline in cognitive function sufficient to affect activities of daily living or social functioning
.

Alzheimer's disease (AD) and vascular dementia are the more common types of dementia, if information on dementia subtypes is available

Blood vessel

Understanding dementia incidence, mortality, associated diseases at the population level, and how patients present and progress in the healthcare system, may be valuable for planning and developing interventions that may be valuable at specific stages of disease development to support individuals and reduce dementia The social burden is necessary
.

A detailed understanding of how, when and why people with dementia enter the healthcare system is still lacking
.

While previous dementia studies have provided insights into disease burden, they have been limited in scope because reports on regional cohorts or surveys cannot provide precise estimates of dementia comorbidities and healthcare resource use

In this way, Sheng-Chia Chung of UCL UK overcomes this limitation by using routinely collected primary electronic health record (EHR) data to link secondary care and death data for 4.
3 million individuals in the UK
.

They investigated morbidity, comorbidities, reasons for clinical visits, mortality, and causes of death
.

Disease patterns in subgroups including gender and poverty were studied

They conducted a longitudinal cohort analysis of connected electronic health records of 4.
3 million people in the UK to investigate dementia morbidity and mortality
.

The causes of hospitalization and causes of death were compared between people with and without dementia

From 1998 to 2016, they observed 145,319 people (3.
1%) with incident dementia
.

Repeated hospitalizations for infections , unknown morbidity, and multiple visits to primary care for chronic pain were observed in older adults prior to dementia diagnosis .

Repeated hospitalizations for infections , unknown morbidity, and multiple visits to primary care for chronic pain were observed in older adults prior to dementia diagnosis .

The significance of the study is the finding that there is considerable variation in dementia, which informs priorities for prevention
and delivery of patient care .

Dementia varies considerably, which informs priorities for prevention and provision of patient care Prevention

Original source:
Chung S, Providencia R, Sofat R, et al.

Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.
3 million individuals.
Alzheimer's & Dementia.

Incidence, morbidity, mortality and disparities in dementia: A population linked electronic health records study of 4.
3 million individuals.
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