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Alzheimer's&Dementia: Here comes the neuroanatomical evidence that the Mediterranean diet prevents Alzheimer's disease!

 Last Update: 2021-05-21
 Source: Internet
 Author: User

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Diet is an important factor that mediates the risk of neurodegenerative diseases.

Mediterranean diet Maintaining a Mediterranean diet can reduce circulating biomarkers of the risk of ischemic heart disease, and is associated with a reduced risk of cardiovascular disease, cognitive impairment and AD.

Although the reasonable biological mechanisms of these effects have been determined, most of these data come from observational studies.

Socioeconomic differences are one of the most obvious drivers of chronic psychosocial stress, and the gradient of health differences caused by stress may become steeper with age.

Low socioeconomic status (SES) increases the risk of dementia, but the basic factors for this difference are not yet clear.

Because diet and socioeconomic status can affect many aspects of health (such as physical activity, diet, education, income, neighbor relations, reserves) are different, which complicates the process of discovering the mechanism.

Researchers used structural magnetic resonance imaging (fMRI) to study the effects of diet (Mediterranean and Western) and social subordinate pressure on brain anatomy in a fully validated neuropathological model similar to AD in non-human primates.

Changes in brain volume of the two groups during the experiment.

In the western group, total brain volume, cortical thickness, and gray matter volume increased significantly, while the volume of cerebrospinal fluid and white matter decreased significantly.

The social status difference of the whole brain volume.

Western diet and psychosocial stress can cause pathological changes and increase the risk of AD-related neuropathology, while the Mediterranean diet may protect the brain.

In summary, if you want to better protect the brain and prevent dementia, a Mediterranean diet and reducing social and psychological stress may be a good choice.

references:

onlinelibrary.

onlinelibrary.
wiley.
com/doi/10.
1002/alz.
12232" target="_blank" rel="noopener">Diet, psychosocial stress, and Alzheimer's disease–related neuroanatomy in female nonhuman primates.

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