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Alzheimers Dement: Patients with dementia are at increased risk of COVID-19

 Last Update: 2021-12-03
 Source: Internet
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There are serious inequalities in age, race, and gender of COVID-19 patients
.

The impact of COVID-19 on blacks is disproportionately high

COVID-19 Patients with COVID-19 have serious inequalities in age, race, and gender

Rong Xu et al.

Rong Xu et al.
conducted a retrospective case-control analysis of patient electronic health records (EHRs) of 61.
9 million adult patients (age ≥18 years) in the United States as of August 21, 2020
.

Adjusting for age, gender, race and COVID-19 risk factors, including asthma, heart vascular disease, cancer, type 2 diabetes , obesity, chronic kidney disease, chronic obstructive pulmonary disease, substance use disorders, transplant procedures (bone marrow, solid organ ) And the status of nursing home accommodation, the incidence of COVID-19 in patients with dementia compared with non-dementia patients

Adjusting for age, gender, race and COVID-19 risk factors, including asthma, heart vascular disease, cancer, type 2 diabetes , obesity, chronic kidney disease, chronic obstructive pulmonary disease, substance use disorders, transplant procedures (bone marrow, solid organ ) and post-stay nursing home situation, dementia COVID-19 compared with the incidence of dementia in patients with non- cardiac vascular diabetes

After adjusting for demographic data (age, gender, race), the incidence of COVID-19 in patients with dementia compared to non-dementia patients
.

Adjusted age, gender, race, and COVID-19 risk factors, including asthma, cardiovascular disease, cancer, type 2 diabetes, obesity, chronic kidney disease, chronic obstructive pulmonary disease, substance use disorder, transplantation procedures (bone marrow, solid organs) ) And the status of nursing home accommodation, the impact of demographics on the incidence of COVID-19 among dementia patients

Compared with non-dementia patients, patients with dementia have a higher risk of COVID-19 (adjusted odds ratio [AOR]: 2.
00 [95% confidence interval (CI), 1.
94-2.
06], P <0.
001), where the impact of vascular dementia The strongest (AOR: 3.
17 [95% CI, 2.
97-3.
37], P <0.
001), followed by Alzheimer's disease (AOR: 2.
62 [95% CI, 2.
28-3.
00], P <0.
001), Alzheimer’s disease (AOR: 1.
86 [95% CI, 1.
77-1.
96], P <0.
001), senile dementia (AOR: 1.
99 [95% CI, 1.
86-2.
13], P <0.
001) and post-traumatic dementia (AOR: 1.
67 [95% CI, 1.
51-1.
86] P <0.
001)
.

Blacks with dementia have a higher risk of COVID-19 than whites (AOR: 2.
86 [95% CI, 2.
67-3.
06], P <0.
001)
.

Patients with dementia (or Alzheimer’s disease [AD]) and COVID-19 at the same time, patients with COVID-19 but no dementia, and patients with dementia (or AD) but no COVID-19 Six-month hospitalization risk and death risk
.

***: P <0.

The 6-month mortality and hospitalization risk of dementia and COVID-19 patients were 20.

Compared with non-dementia patients, patients with dementia have a significantly increased risk of COVID-19

Wang, Q.

Wang, Q.
et al.
COVID-19 and dementia: analyses of risk, disparity, and outcomes from electronic health records in the US.
Alzheimers Dement.
Wang, Q.
et al.
COVID-19 and dementia: analyses of risk, disparity , and outcomes from electronic health records in the US.
Alzheimers Dement.
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