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Alzheimers Dement: Elderly people with high resting heart rate have rapid cognitive decline and high risk of dementia

 Last Update: 2021-12-26
 Source: Internet
 Author: User

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A large amount of evidence consistently shows that rising resting heart rate (RHR) is more predictive of future CVD events than traditional CVD risk factors
.

A limited number of studies have also shown that high RHR is associated with cognitive decline and dementia in middle-aged people and patients with ischemic stroke

Blood vessel

Yume Imahori et al.
investigated the relationship between elevated RHR and the incidence of dementia in the elderly
.

It is assumed that elevated RHR is associated with an increased risk of dementia and cognitive decline in the elderly, and their correlation may be independent of cardiovascular risk factors and cardiovascular disease

This population-based cohort study included 2147 participants over the age of 60 who were dementia-free from 2001-2004 to 2013-2016 and were followed up regularly
.

Evaluate RHR with ECG

Diagnostic statistics

RHR≥80 (vs.
60-69) bpm is associated with a multiple adjusted hazard ratio of 1.
55 (95% confidence interval 1.
06-2.
27) for dementia
.

After excluding participants from epidemic and sudden cardiovascular diseases, the correlation is still significant

RHR≥80 (vs.

In this prospective cohort study based on the elderly in Sweden, it was found that RHR ≥ 80 bpm was associated with an increased risk of dementia within 12 years, and was not related to vascular risk factors and underlying cardiovascular disease
.

After excluding participants with epidemic and sudden cardiovascular diseases, this correlation is still significant, and cardiovascular disease is a known risk factor for dementia

High
RHR is associated with increased risk of Alzheimer’s disease and accelerated global cognitive decline, and has nothing to do with major cardiovascular risk factors and cardiovascular disease .

Further research is needed to confirm our results and explore the mechanism of this association

RHR High RHR is associated with increased risk of Alzheimer’s disease and accelerated global cognitive decline, and has nothing to do with major cardiovascular risk factors and cardiovascular disease

Imahori Y, Vetrano DL, Xia X, et al.

Imahori Y, Vetrano DL, Xia X, et al.
Association of resting heart rate with cognitive decline and dementia in older adults: A population-based cohort study [published online ahead of print, 2021 Dec 3].
Alzheimers Dement.
2021;10.
1002 /alz.
12495.
doi:10.
1002/alz.
12495 leave a message here

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