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Alzheimer Dementia: Oh my god!

 Last Update: 2021-12-26
 Source: Internet
 Author: User

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Loneliness is a subjective feeling that stems from the perceived difference between expected and actual social relationships

Although loneliness itself does not have a state of clinical disease, it is related to a series of negative health outcomes, including stress, sleep disorders, depressive symptoms, cognitive impairment, coronary heart disease, stroke, and mortality

However, the relationship between loneliness and dementia is unclear

A person’s experience of loneliness may change.

In order to comprehensively analyze the above problems, psychologists from the Massachusetts General Hospital in the United States have carried out relevant research, mainly analyzing the relationship between different types of middle-aged loneliness and the development of dementia and AD.

Researchers used an item in the Depression Scale of the Center for Epidemiology to assess the loneliness of cognitively normal adults

Framingham Heart Study ( FHS ) data

The results showed that after adjusting for demographics, social networks, physical health, and apolipoprotein Eε4, the scores of persistent loneliness and dementia nearly doubled (HR=1.

Persistent loneliness is associated with nearly doubling the dementia score (HR=1.

Analysis of cumulative rate of dementia and Alzheimer's disease (AD) based on loneliness and log-rank test analysis

It can be seen that persistent loneliness in middle age is an independent risk factor for dementia and AD, and recovery from loneliness indicates resilience to the risk of dementia

references:

Associations of loneliness with risk of Alzheimer's disease dementia in the Framingham Heart Study.

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